Browsing byAuthorUmashankar, B

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Showing results 1 to 6 of 6
Issue DateTitleAuthor(s)
2019-03-01Aryl-urea fatty acids that activate the p38 MAP kinase and down-regulate multiple cyclins decrease the viability of MDA-MB-231 breast cancer cellsAl-Zubaidi, Y; Pazderka, C; Koolaji, N; Rahman, MK; Choucair, H; Umashankar, B; Bourget, K; Chen, Y; Rawling, T; Murray, M
2023-01-15Inclusion of the in-chain sulfur in 3-thiaCTU increases the efficiency of mitochondrial targeting and cell killing by anticancer aryl-urea fatty acids.Rahman, MK; Umashankar, B; Choucair, H; Pazderka, C; Bourget, K; Chen, Y; Dunstan, CR; Rawling, T; Murray, M
2021-10PTU, a novel ureido-fatty acid, inhibits MDA-MB-231 cell invasion and dissemination by modulating Wnt5a secretion and cytoskeletal signaling.Al-Zubaidi, Y; Chen, Y; Khalilur Rahman, M; Umashankar, B; Choucair, H; Bourget, K; Chung, L; Qi, Y; Witting, PK; Anderson, RL; O'Neill, GM; Dunstan, CR; Rawling, T; Murray, M
2022-02-01The aryl-ureido fatty acid CTU activates endoplasmic reticulum stress and PERK/NOXA-mediated apoptosis in tumor cells by a dual mitochondrial-targeting mechanism.Choucair, H; Rahman, MK; Umashankar, B; Al-Zubaidi, Y; Bourget, K; Chen, Y; Dunstan, C; Rawling, T; Murray, M
2024-06The inositol-requiring enzyme 1 (IRE1) endoplasmic reticulum stress pathway promotes MDA-MB-231 cell survival and renewal in response to the aryl-ureido fatty acid CTU.Rahman, MK; Umashankar, B; Choucair, H; Bourget, K; Rawling, T; Murray, M
2024-10-01The Novel Anticancer Aryl-Ureido Fatty Acid CTU Increases Reactive Oxygen Species Production That Impairs Mitochondrial Fusion Mechanisms and Promotes MDA-MB-231 Cell Death.Tam, S; Umashankar, B; Rahman, MK; Choucair, H; Rawling, T; Murray, M