Applications of protein-based capacitive biosensors for the detection of heavy-metal ions
- Publication Type:
- Conference Proceeding
- Citation:
- Proceedings of the 2006 International Conference on Nanoscience and Nanotechnology, ICONN, 2006, pp. 235 - 238
- Issue Date:
- 2006-12-01
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2009004503OK.pdf | 1.96 MB |
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Three different methods of using protein-based capacitive biosensors for the detection of heavy-metal ions are presented. The metal-binding proteins SmtA, S100A12, MerP and four modified MerPs were immobilised as the biorecognition element on self-assembled monolayer-modified gold electrodes. Capacitance was measured using potential square step or electrical impedance spectroscopy. The protein-metal interaction generated changes in capacitance mainly due to a protein conformational change. © 2006 IEEE.
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