The use of psychotropic agents for the symptoms of obsessive-compulsive disorder

Brakoulias, V; Starcevic, V; Berle, D; Milicevic, D; Moses, K; Hannan, A; Sammut, P; Martin, A

The use of psychotropic agents for the symptoms of obsessive-compulsive disorder

Brakoulias, V Starcevic, V Berle, D

Milicevic, D Moses, K Hannan, A Sammut, P Martin, A

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Publication Type:: Journal Article
Citation:: Australasian Psychiatry, 2013, 21 (2), pp. 117 - 121
Issue Date:: 2013-01-01

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Field	Value	Language
dc.contributor.author	Brakoulias, V	en_US
dc.contributor.author	Starcevic, V	en_US
dc.contributor.author	Berle, D https://orcid.org/0000-0002-4861-2220	en_US
dc.contributor.author	Milicevic, D	en_US
dc.contributor.author	Moses, K	en_US
dc.contributor.author	Hannan, A	en_US
dc.contributor.author	Sammut, P	en_US
dc.contributor.author	Martin, A	en_US
dc.date.issued	2013-01-01	en_US
dc.identifier.citation	Australasian Psychiatry, 2013, 21 (2), pp. 117 - 121	en_US
dc.identifier.issn	1039-8562	en_US
dc.identifier.uri	http://hdl.handle.net/10453/117122
dc.description.abstract	Objective: To describe the use of psychotropic agents in a sample of subjects with obsessive-compulsive disorder (OCD), and in particular the differences associated with different OCD symptoms. Method: A total of 154 subjects participated in a study assessing OCD symptom subtypes, called the Nepean OCD Study. In addition to a comprehensive evaluation of the subjects' OCD symptoms using the Yale-Brown Obsessive-Compulsive Scale (Y-BOCS), Vancouver Obsessive-Compulsive Inventory (VOCI), and the Sheehan Disability Scale (SDS), the subjects' medication history was recorded. The association between symptom severity, disability, OCD symptom subtypes and the use of psychotropic agents was examined. Results: Psychotropic medication was taken by 93 (60.4%) participants. In the majority of cases (n=55, 59.1%), selective serotonin reuptake inhibitors (SSRIs) were taken, and of the SSRIs, the most commonly used agent was escitalopram (n=21, 22.6%). Psychotropic agents were more likely to be taken by subjects with higher Y-BOCS and SDS scores. Hoarding was associated with a lower likelihood of psychotropic use, whereas unacceptable/taboo thoughts were associated with an increased likelihood of psychotropic and antipsychotic use. Conclusion: Patients with OCD are more likely to be taking psychotropic agents if they have a more severe illness, greater disability and more prominent unacceptable/taboo thoughts. © The Royal Australian and New Zealand College of Psychiatrists 2013.	en_US
dc.relation.ispartof	Australasian Psychiatry	en_US
dc.relation.isbasedon	10.1177/1039856212470502	en_US
dc.subject.classification	Psychiatry	en_US
dc.subject.mesh	Humans	en_US
dc.subject.mesh	Psychotropic Drugs	en_US
dc.subject.mesh	Obsessive-Compulsive Disorder	en_US
dc.subject.mesh	Psychiatric Status Rating Scales	en_US
dc.subject.mesh	Adolescent	en_US
dc.subject.mesh	Adult	en_US
dc.subject.mesh	Drug Utilization	en_US
dc.title	The use of psychotropic agents for the symptoms of obsessive-compulsive disorder	en_US
dc.type	Journal Article
utslib.citation.volume	2	en_US
utslib.citation.volume	21	en_US
utslib.for	1701 Psychology	en_US
utslib.for	11 Medical and Health Sciences	en_US
utslib.for	17 Psychology and Cognitive Sciences	en_US
pubs.embargo.period	Not known	en_US
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Graduate School of Health
utslib.copyright.status	closed_access
pubs.issue	2	en_US
pubs.publication-status	Published	en_US
pubs.volume	21	en_US

Abstract:

Objective: To describe the use of psychotropic agents in a sample of subjects with obsessive-compulsive disorder (OCD), and in particular the differences associated with different OCD symptoms. Method: A total of 154 subjects participated in a study assessing OCD symptom subtypes, called the Nepean OCD Study. In addition to a comprehensive evaluation of the subjects' OCD symptoms using the Yale-Brown Obsessive-Compulsive Scale (Y-BOCS), Vancouver Obsessive-Compulsive Inventory (VOCI), and the Sheehan Disability Scale (SDS), the subjects' medication history was recorded. The association between symptom severity, disability, OCD symptom subtypes and the use of psychotropic agents was examined. Results: Psychotropic medication was taken by 93 (60.4%) participants. In the majority of cases (n=55, 59.1%), selective serotonin reuptake inhibitors (SSRIs) were taken, and of the SSRIs, the most commonly used agent was escitalopram (n=21, 22.6%). Psychotropic agents were more likely to be taken by subjects with higher Y-BOCS and SDS scores. Hoarding was associated with a lower likelihood of psychotropic use, whereas unacceptable/taboo thoughts were associated with an increased likelihood of psychotropic and antipsychotic use. Conclusion: Patients with OCD are more likely to be taking psychotropic agents if they have a more severe illness, greater disability and more prominent unacceptable/taboo thoughts. © The Royal Australian and New Zealand College of Psychiatrists 2013.

Please use this identifier to cite or link to this item:

http://hdl.handle.net/10453/117122