Biochemical and physiological responses of halophilic nanophytoplankton (Dunaliella salina) from exposure to xeno-estrogen 17α-ethinylestradiol

Belhaj, D; Athmouni, K; Frikha, D; Kallel, M; El Feki, A; Maalej, S; Zhou, JL; Ayadi, H

Biochemical and physiological responses of halophilic nanophytoplankton (Dunaliella salina) from exposure to xeno-estrogen 17α-ethinylestradiol

Belhaj, D Athmouni, K Frikha, D Kallel, M El Feki, A Maalej, S Zhou, JL

Ayadi, H

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Publication Type:: Journal Article
Citation:: Environmental Science and Pollution Research, 2017, 24 (8), pp. 7392 - 7402
Issue Date:: 2017-03-01

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Field	Value	Language
dc.contributor.author	Belhaj, D	en_US
dc.contributor.author	Athmouni, K	en_US
dc.contributor.author	Frikha, D	en_US
dc.contributor.author	Kallel, M	en_US
dc.contributor.author	El Feki, A	en_US
dc.contributor.author	Maalej, S	en_US
dc.contributor.author	Zhou, JL https://orcid.org/0000-0003-1393-1608	en_US
dc.contributor.author	Ayadi, H	en_US
dc.date.available	2017-01-05	en_US
dc.date.issued	2017-03-01	en_US
dc.identifier.citation	Environmental Science and Pollution Research, 2017, 24 (8), pp. 7392 - 7402	en_US
dc.identifier.issn	0944-1344	en_US
dc.identifier.uri	http://hdl.handle.net/10453/117711
dc.description.abstract	© 2017, Springer-Verlag Berlin Heidelberg. The environmental impacts of various pollutants on the entire levels of organisms are under investigation. Among these pollutants, endocrine-disrupting compounds (EDCs) present a serious hazard, even though the environmental significance of these compounds remains basically unknown. To drop some light on this field, we assessed the effects of a 11-day exposure of 17α-ethinylestradiol (EE2) on the growth, metabolic content, antioxidant response, oxidative stress, and genetic damage of Dunaliella salina, isolated from Tunisian biotopes. The results showed that at 10 ng L−1, EE2 could stimulate the growth of D. salina and increase its cellular content of photosynthetic pigments and metabolites; however, it did not significantly increase the activities of superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx) or the level of malondialdehyde (MDA) and hydrogen peroxide (H2O2). In contrast, exposure to high levels of EE2 concentrations significantly inhibited the growth of D. salina (P < 0.05), decreased the cellular content of photosynthetic pigments, increased the cellular content of all of the metabolites and the SOD activity, and inhibited CAT and GPx activities. Nevertheless, the balance between oxidant and antioxidant enzymes was disrupted because H2O2 content along with MDA content simultaneously increased. Contrary to expected results, DNA damage (strand breaks) decreased after the exposure of algae to EE2. The results of this study suggest that EE2 toxicity could result in environmental impacts with consequences on the whole aquatic community. [Figure not available: see fulltext.]	en_US
dc.relation.ispartof	Environmental Science and Pollution Research	en_US
dc.relation.isbasedon	10.1007/s11356-017-8415-9	en_US
dc.subject.classification	Environmental Sciences	en_US
dc.subject.mesh	Ethinyl Estradiol	en_US
dc.subject.mesh	Water Pollutants, Chemical	en_US
dc.subject.mesh	Environmental Monitoring	en_US
dc.subject.mesh	Oxidative Stress	en_US
dc.subject.mesh	Endocrine Disruptors	en_US
dc.subject.mesh	Chlorophyta	en_US
dc.title	Biochemical and physiological responses of halophilic nanophytoplankton (Dunaliella salina) from exposure to xeno-estrogen 17α-ethinylestradiol	en_US
dc.type	Journal Article
utslib.citation.volume	8	en_US
utslib.citation.volume	24	en_US
utslib.for	0305 Organic Chemistry	en_US
utslib.for	0501 Ecological Applications	en_US
utslib.for	0601 Biochemistry and Cell Biology	en_US
utslib.for	03 Chemical Sciences	en_US
utslib.for	05 Environmental Sciences	en_US
utslib.for	06 Biological Sciences	en_US
pubs.embargo.period	Not known	en_US
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Engineering and Information Technology
pubs.organisational-group	/University of Technology Sydney/Faculty of Engineering and Information Technology/School of Civil and Environmental Engineering
pubs.organisational-group	/University of Technology Sydney/Strength - CTWW - Centre for Technology in Water and Wastewater Treatment
utslib.copyright.status	open_access
pubs.issue	8	en_US
pubs.publication-status	Published	en_US
pubs.volume	24	en_US

Abstract:

© 2017, Springer-Verlag Berlin Heidelberg. The environmental impacts of various pollutants on the entire levels of organisms are under investigation. Among these pollutants, endocrine-disrupting compounds (EDCs) present a serious hazard, even though the environmental significance of these compounds remains basically unknown. To drop some light on this field, we assessed the effects of a 11-day exposure of 17α-ethinylestradiol (EE2) on the growth, metabolic content, antioxidant response, oxidative stress, and genetic damage of Dunaliella salina, isolated from Tunisian biotopes. The results showed that at 10 ng L−1, EE2 could stimulate the growth of D. salina and increase its cellular content of photosynthetic pigments and metabolites; however, it did not significantly increase the activities of superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx) or the level of malondialdehyde (MDA) and hydrogen peroxide (H2O2). In contrast, exposure to high levels of EE2 concentrations significantly inhibited the growth of D. salina (P < 0.05), decreased the cellular content of photosynthetic pigments, increased the cellular content of all of the metabolites and the SOD activity, and inhibited CAT and GPx activities. Nevertheless, the balance between oxidant and antioxidant enzymes was disrupted because H2O2 content along with MDA content simultaneously increased. Contrary to expected results, DNA damage (strand breaks) decreased after the exposure of algae to EE2. The results of this study suggest that EE2 toxicity could result in environmental impacts with consequences on the whole aquatic community. [Figure not available: see fulltext.]

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http://hdl.handle.net/10453/117711