Attitudes of sperm, egg and embryo donors and recipients towards genetic information and screening of donors

Amor, DJ; Kerr, A; Somanathan, N; McEwen, A; Tome, M; Hodgson, J; Lewis, S

Attitudes of sperm, egg and embryo donors and recipients towards genetic information and screening of donors

Amor, DJ Kerr, A Somanathan, N McEwen, A

Tome, M Hodgson, J Lewis, S

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Publication Type:: Journal Article
Citation:: Reproductive Health, 2018, 15 (1)
Issue Date:: 2018-02-09

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Field	Value	Language
dc.contributor.author	Amor, DJ	en_US
dc.contributor.author	Kerr, A	en_US
dc.contributor.author	Somanathan, N	en_US
dc.contributor.author	McEwen, A https://orcid.org/0000-0001-8705-1190	en_US
dc.contributor.author	Tome, M	en_US
dc.contributor.author	Hodgson, J	en_US
dc.contributor.author	Lewis, S	en_US
dc.date.available	2018-01-29	en_US
dc.date.issued	2018-02-09	en_US
dc.identifier.citation	Reproductive Health, 2018, 15 (1)	en_US
dc.identifier.uri	http://hdl.handle.net/10453/128498
dc.description.abstract	© 2018 The Author(s). Background: Gamete and embryo donors undergo genetic screening procedures in order to maximise the health of donor-conceived offspring. In the era of genomic medicine, expanded genetic screening may be offered to donors for the purpose of avoiding transmission of harmful genetic mutations. The objective of this study was to explore the attitudes of donors and recipients toward the expanded genetic screening of donors. Methods: Qualitative interview study with thematic analysis, undertaken in a tertiary fertility centre. Semi-structured in-depth qualitative interviews were conducted with eleven recipients and nine donors from three different cohorts (sperm, egg and embryo donors/recipients). Results: Donors and recipients acknowledged the importance of genetic information and were comfortable with the existing level of genetic screening of donors. Recipients recognised some potential benefits of expanded genetic screening of donors; however both recipients and donors were apprehensive about extended genomic technologies, with concerns about how this information would be used and the ethics of genetic selectivity. Conclusion: Participants in donor programs support some level of genetic screening of donors, but are wary of expanding genetic screening beyond current levels.	en_US
dc.relation.ispartof	Reproductive Health	en_US
dc.relation.isbasedon	10.1186/s12978-018-0468-9	en_US
dc.subject.classification	Obstetrics & Reproductive Medicine	en_US
dc.subject.mesh	Spermatozoa	en_US
dc.subject.mesh	Humans	en_US
dc.subject.mesh	Insemination, Artificial, Heterologous	en_US
dc.subject.mesh	Oocyte Donation	en_US
dc.subject.mesh	Attitude to Health	en_US
dc.subject.mesh	Family Characteristics	en_US
dc.subject.mesh	Genetic Privacy	en_US
dc.subject.mesh	Tissue Donors	en_US
dc.subject.mesh	Female	en_US
dc.subject.mesh	Male	en_US
dc.subject.mesh	Embryo, Mammalian	en_US
dc.subject.mesh	Genetic Testing	en_US
dc.title	Attitudes of sperm, egg and embryo donors and recipients towards genetic information and screening of donors	en_US
dc.type	Journal Article
utslib.citation.volume	1	en_US
utslib.citation.volume	15	en_US
utslib.for	1114 Paediatrics and Reproductive Medicine	en_US
pubs.embargo.period	Not known	en_US
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Graduate School of Health
utslib.copyright.status	open_access
pubs.issue	1	en_US
pubs.publication-status	Published	en_US
pubs.volume	15	en_US

Abstract:

© 2018 The Author(s). Background: Gamete and embryo donors undergo genetic screening procedures in order to maximise the health of donor-conceived offspring. In the era of genomic medicine, expanded genetic screening may be offered to donors for the purpose of avoiding transmission of harmful genetic mutations. The objective of this study was to explore the attitudes of donors and recipients toward the expanded genetic screening of donors. Methods: Qualitative interview study with thematic analysis, undertaken in a tertiary fertility centre. Semi-structured in-depth qualitative interviews were conducted with eleven recipients and nine donors from three different cohorts (sperm, egg and embryo donors/recipients). Results: Donors and recipients acknowledged the importance of genetic information and were comfortable with the existing level of genetic screening of donors. Recipients recognised some potential benefits of expanded genetic screening of donors; however both recipients and donors were apprehensive about extended genomic technologies, with concerns about how this information would be used and the ethics of genetic selectivity. Conclusion: Participants in donor programs support some level of genetic screening of donors, but are wary of expanding genetic screening beyond current levels.

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http://hdl.handle.net/10453/128498