Combined use of the chemitrode with osmotic minipumps for experimental brain research

Girgis, M; Kent, JC; Kohlhardt, S; Rasko, J; Stobo, P

Combined use of the chemitrode with osmotic minipumps for experimental brain research

Girgis, M Kent, JC Kohlhardt, S Rasko, J Stobo, P

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Publisher:: Elsevier
Publication Type:: Journal Article
Citation:: Brain Research Bulletin, 1981, 7 (6), pp. 719 - 721
Issue Date:: 1981-01

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Field	Value	Language
dc.contributor.author	Girgis, M
dc.contributor.author	Kent, JC
dc.contributor.author	Kohlhardt, S
dc.contributor.author	Rasko, J
dc.contributor.author	Stobo, P
dc.date.accessioned	2011-02-07T06:24:36Z
dc.date.issued	1981-01
dc.identifier.citation	Brain Research Bulletin, 1981, 7 (6), pp. 719 - 721
dc.identifier.issn	0361-9230
dc.identifier.other	C1UNSUBMIT	en_US
dc.identifier.uri	http://hdl.handle.net/10453/13772
dc.description.abstract	This paper describes a simple-to-build minipump-chemitrode assembly which can be used for long term electrophysiological, chemical and behavioural studies. This system consists of an osmotic minipump, a cannula and an array of nine electrodes which are connected to a miniature Winchester Socket. A detailed plan for construction of both the chemitrode and the minipump-chemitrode is given together with some suggestions for possible usages in brain research(such as kindling). The osmotic minipump consists of a collapsible reservoir of flexible, impermeable material, surrounded by a sealed layer containing an osmotic agent--all of which is contained by a semipermeable membrane. Imbibed water generates hydrostatic pressure on the flexible lining of the reservoir, gradually compressing it, producing a constant flow of its contents through the delivery portal.
dc.publisher	Elsevier
dc.relation.ispartof	Brain Research Bulletin
dc.relation.ispartof	Verified OK	en_US
dc.relation.isbasedon	10.1016/0361-9230(81)90125-8
dc.subject	Minipump-chemitrode, Behaviour, Kindling, Prostigmine, Reserpine, Neurology & Neurosurgery
dc.subject	Minipump-chemitrode; Behaviour; Kindling; Prostigmine; Reserpine	en_US
dc.subject	Minipump-chemitrode
dc.subject	Minipump-chemitrode; Behaviour; Kindling; Prostigmine; Reserpine; Neurology & Neurosurgery
dc.subject	Behaviour
dc.subject	Kindling
dc.subject	Prostigmine
dc.subject	Reserpine
dc.subject.classification	Neurosciences	en_US
dc.title	Combined use of the chemitrode with osmotic minipumps for experimental brain research
dc.type	Journal article
utslib.citation.volume	6
utslib.citation.volume	7
utslib.citation.number	6	en_US
utslib.location	The Netherlands	en_US
utslib.citation.startpage	719	en_US
utslib.citation.endpage	721	en_US
utslib.identifier.org	DVCRch.Institute for Sustainable Futures	en_US
utslib.for	1109 Neurosciences
utslib.percentage	100	en_US
pubs.embargo.period	Not known
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/DVC (Research)
pubs.organisational-group	/University of Technology Sydney/DVC (Research)/Institute For Sustainable Futures
utslib.copyright.status	closed_access
pubs.declined	1970-01-01T00:00:00.0+1000

Abstract:

This paper describes a simple-to-build minipump-chemitrode assembly which can be used for long term electrophysiological, chemical and behavioural studies. This system consists of an osmotic minipump, a cannula and an array of nine electrodes which are connected to a miniature Winchester Socket. A detailed plan for construction of both the chemitrode and the minipump-chemitrode is given together with some suggestions for possible usages in brain research(such as kindling). The osmotic minipump consists of a collapsible reservoir of flexible, impermeable material, surrounded by a sealed layer containing an osmotic agent--all of which is contained by a semipermeable membrane. Imbibed water generates hydrostatic pressure on the flexible lining of the reservoir, gradually compressing it, producing a constant flow of its contents through the delivery portal.

Please use this identifier to cite or link to this item:

http://hdl.handle.net/10453/13772