Red blood cells as an efficient in vitro model for evaluating the efficacy of metallic nanoparticles

Wadhwa, R; Aggarwal, T; Thapliyal, N; Kumar, A; Priya; Yadav, P; Kumari, V; Reddy, BSC; Chandra, P; Maurya, PK

Red blood cells as an efficient in vitro model for evaluating the efficacy of metallic nanoparticles

Wadhwa, R Aggarwal, T Thapliyal, N Kumar, A Priya Yadav, P Kumari, V Reddy, BSC Chandra, P Maurya, PK

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Publication Type:: Journal Article
Citation:: 3 Biotech, 2019, 9 (7)
Issue Date:: 2019-07-01

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Field	Value	Language
dc.contributor.author	Wadhwa, R	en_US
dc.contributor.author	Aggarwal, T	en_US
dc.contributor.author	Thapliyal, N	en_US
dc.contributor.author	Kumar, A	en_US
dc.contributor.author	Priya	en_US
dc.contributor.author	Yadav, P	en_US
dc.contributor.author	Kumari, V	en_US
dc.contributor.author	Reddy, BSC	en_US
dc.contributor.author	Chandra, P	en_US
dc.contributor.author	Maurya, PK	en_US
dc.date.issued	2019-07-01	en_US
dc.identifier.citation	3 Biotech, 2019, 9 (7)	en_US
dc.identifier.issn	2190-572X	en_US
dc.identifier.uri	http://hdl.handle.net/10453/137956
dc.description.abstract	© 2019, King Abdulaziz City for Science and Technology. Blood and the linings of blood vessels may be regarded as a fifth tissue type. The human body contains 5 × 109 red blood cells (RBCs) per ml, a total of 2.5 × 1013 cells in the 5 l of blood present in the body. With an average lifetime of 125 days, human RBCs are destroyed by leukocytes in the spleen and liver. Nowadays red blood cells are extensively used to study various metabolic functions. Nanoparticles (NP) are being widely accepted for drug delivery system. This review summarizes the red blood cells, NPs and their characteristics on the basis of the RBC components along with drug delivery systems through RBCs. Further, we also discussed that how erythrocytes can be used as an efficient in vitro model for evaluating the efficacy of various nanocomposite materials.	en_US
dc.relation.ispartof	3 Biotech	en_US
dc.relation.isbasedon	10.1007/s13205-019-1807-4	en_US
dc.title	Red blood cells as an efficient in vitro model for evaluating the efficacy of metallic nanoparticles	en_US
dc.type	Journal Article
utslib.citation.volume	7	en_US
utslib.citation.volume	9	en_US
utslib.for	0601 Biochemistry and Cell Biology	en_US
utslib.for	1007 Nanotechnology	en_US
pubs.embargo.period	Not known	en_US
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Graduate School of Health
pubs.organisational-group	/University of Technology Sydney/Students
utslib.copyright.status	closed_access
pubs.issue	7	en_US
pubs.publication-status	Published	en_US
pubs.volume	9	en_US

Abstract:

© 2019, King Abdulaziz City for Science and Technology. Blood and the linings of blood vessels may be regarded as a fifth tissue type. The human body contains 5 × 109 red blood cells (RBCs) per ml, a total of 2.5 × 1013 cells in the 5 l of blood present in the body. With an average lifetime of 125 days, human RBCs are destroyed by leukocytes in the spleen and liver. Nowadays red blood cells are extensively used to study various metabolic functions. Nanoparticles (NP) are being widely accepted for drug delivery system. This review summarizes the red blood cells, NPs and their characteristics on the basis of the RBC components along with drug delivery systems through RBCs. Further, we also discussed that how erythrocytes can be used as an efficient in vitro model for evaluating the efficacy of various nanocomposite materials.

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http://hdl.handle.net/10453/137956