Fluidisation characteristics of lactose powders in simple turbulent channel flows

Mahmoudi, S; Elserfy, K; Cheng, S; Chan, HK; Hebbink, G; Kourmatzis, A

Fluidisation characteristics of lactose powders in simple turbulent channel flows

Mahmoudi, S Elserfy, K Cheng, S Chan, HK Hebbink, G Kourmatzis, A

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Publication Type:: Journal Article
Citation:: Experimental Thermal and Fluid Science, 2019, 103 pp. 201 - 213
Issue Date:: 2019-05-01

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Field	Value	Language
dc.contributor.author	Mahmoudi, S	en_US
dc.contributor.author	Elserfy, K	en_US
dc.contributor.author	Cheng, S	en_US
dc.contributor.author	Chan, HK	en_US
dc.contributor.author	Hebbink, G	en_US
dc.contributor.author	Kourmatzis, A	en_US
dc.date.accessioned	2020-03-27T01:04:00Z
dc.date.available	2020-03-27T01:04:00Z
dc.date.issued	2019-05-01	en_US
dc.identifier.citation	Experimental Thermal and Fluid Science, 2019, 103 pp. 201 - 213	en_US
dc.identifier.issn	0894-1777	en_US
dc.identifier.uri	http://hdl.handle.net/10453/139559
dc.description.abstract	© 2019 Elsevier Inc. A new experimental platform is presented which enables investigation of the effects of turbulence, mean forces and powder properties on the fluidisation of lactose powders as relevant to pharmaceutical applications. The flow consists of a fully developed channel flow which delivers a well-defined velocity profile over a bed of powder. An in-house two beam line of sight attenuation method has been developed to extract quantitative information on powder fluidisation time, time-resolved fluctuations in powder concentration and frequencies associated with the powder fluidisation process. Four lactose powders are examined which have a range of mass mean diameters and cohesiveness. Reynolds numbers from approximately 9000 to 20,000 are examined in this study, representing one of a few quantitative examinations of lactose powder behaviour in a simple canonical flow, where the boundary conditions are well-defined and the flow is intentionally simple. Evacuation times show dependence on the Reynolds number varied both through changing the local velocity and channel dimension, whereas the Reynolds number dependence weakens at higher Reynolds numbers. Frequencies measured show physical consistency with theoretical frequencies defined through the turbulent velocity and characteristic length-scale of the powder pocket.	en_US
dc.relation.ispartof	Experimental Thermal and Fluid Science	en_US
dc.relation.isbasedon	10.1016/j.expthermflusci.2019.01.012	en_US
dc.subject.classification	Mechanical Engineering & Transports	en_US
dc.title	Fluidisation characteristics of lactose powders in simple turbulent channel flows	en_US
dc.type	Journal Article
utslib.citation.volume	103	en_US
utslib.for	09 Engineering	en_US
pubs.embargo.period	Not known	en_US
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Engineering and Information Technology
utslib.copyright.status	closed_access
pubs.publication-status	Published	en_US
pubs.volume	103	en_US

Abstract:

© 2019 Elsevier Inc. A new experimental platform is presented which enables investigation of the effects of turbulence, mean forces and powder properties on the fluidisation of lactose powders as relevant to pharmaceutical applications. The flow consists of a fully developed channel flow which delivers a well-defined velocity profile over a bed of powder. An in-house two beam line of sight attenuation method has been developed to extract quantitative information on powder fluidisation time, time-resolved fluctuations in powder concentration and frequencies associated with the powder fluidisation process. Four lactose powders are examined which have a range of mass mean diameters and cohesiveness. Reynolds numbers from approximately 9000 to 20,000 are examined in this study, representing one of a few quantitative examinations of lactose powder behaviour in a simple canonical flow, where the boundary conditions are well-defined and the flow is intentionally simple. Evacuation times show dependence on the Reynolds number varied both through changing the local velocity and channel dimension, whereas the Reynolds number dependence weakens at higher Reynolds numbers. Frequencies measured show physical consistency with theoretical frequencies defined through the turbulent velocity and characteristic length-scale of the powder pocket.

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http://hdl.handle.net/10453/139559