Judgment and decision making in genome sequencing

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Clinical Genome Sequencing: Psychological Considerations, 2019, pp. 57 - 73
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© 2019 Elsevier Inc. All rights reserved. Genome sequencing involves a host of decisions on the part of the provider and client, including whether to be tested, when and how to receive sequencing results, whether to inform biological relatives, and whether to take protective actions to reduce risk. In this chapter, we consider the relevance of research in the decision sciences to decisions in the genome sequencing context. We review the role of cognitive factors (e.g., use of heuristics, low numeracy), affective factors (e.g., incidental emotions, affective forecasting), and motivational factors (e.g., regarding oneself positively, adhering to social norms) in judgment and decision-making. In so doing, we consider how knowledge of these factors might inform practice toward the end of improving preference-based decision-making regarding the results of genome sequencing.
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