Role of Oxidative Stress in Complexity of Respiratory Diseases

Ghadiri, M; Yung, AE; Haghi, M

Role of Oxidative Stress in Complexity of Respiratory Diseases

Ghadiri, M Yung, AE Haghi, M

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Publisher:: Springer Nature
Publication Type:: Chapter
Citation:: Role of Oxidative Stress in Pathophysiology of Diseases, 2020, pp. 67-92
Issue Date:: 2020-04-20

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Field	Value	Language
dc.contributor.author	Ghadiri, M
dc.contributor.author	Yung, AE
dc.contributor.author	Haghi, M https://orcid.org/0000-0002-3362-1845
dc.contributor.editor	Maurya, P
dc.contributor.editor	Dua, K
dc.date.accessioned	2021-02-10T20:39:05Z
dc.date.available	2021-02-10T20:39:05Z
dc.date.issued	2020-04-20
dc.identifier.citation	Role of Oxidative Stress in Pathophysiology of Diseases, 2020, pp. 67-92
dc.identifier.isbn	9811515689
dc.identifier.isbn	9789811515682
dc.identifier.uri	http://hdl.handle.net/10453/146025
dc.description.abstract	© Springer Nature Singapore Pte Ltd. 2020. Oxidative stress can arise from excess production of endogenous reactive oxygen species (ROS) or from exposure to exogenous ROS. In the lungs, oxidative stress causes lipid, protein and DNA oxidation, changes to histone acetylation, and inflammation. These pathways are thought to underlay the pathophysiology of respiratory diseases such as asthma, chronic obstructive pulmonary disease, cystic fibrosis, acute respiratory distress syndrome, pneumonia, lung cancer, and obstructive sleep apnoea. This chapter discusses the risk factors for respiratory disease, the evidence for the role of oxidative stress in these diseases, and proposed antioxidant therapies for the treatment of respiratory disease.
dc.language	en
dc.publisher	Springer Nature
dc.relation.ispartof	Role of Oxidative Stress in Pathophysiology of Diseases
dc.relation.isbasedon	10.1007/978-981-15-1568-2_5
dc.rights	info:eu-repo/semantics/closedAccess
dc.title	Role of Oxidative Stress in Complexity of Respiratory Diseases
dc.type	Chapter
pubs.organisational-group	/University of Technology Sydney/Faculty of Health
pubs.organisational-group	/University of Technology Sydney/Faculty of Health/Graduate School of Health/GSH.Pharmacy
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Health/Graduate School of Health
utslib.copyright.status	closed_access	*
pubs.consider-herdc	false
dc.date.updated	2021-02-10T20:38:54Z
pubs.publication-status	Published

Abstract:

© Springer Nature Singapore Pte Ltd. 2020. Oxidative stress can arise from excess production of endogenous reactive oxygen species (ROS) or from exposure to exogenous ROS. In the lungs, oxidative stress causes lipid, protein and DNA oxidation, changes to histone acetylation, and inflammation. These pathways are thought to underlay the pathophysiology of respiratory diseases such as asthma, chronic obstructive pulmonary disease, cystic fibrosis, acute respiratory distress syndrome, pneumonia, lung cancer, and obstructive sleep apnoea. This chapter discusses the risk factors for respiratory disease, the evidence for the role of oxidative stress in these diseases, and proposed antioxidant therapies for the treatment of respiratory disease.

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http://hdl.handle.net/10453/146025