Lanthanide complexes for drug delivery and therapeutics

Bao, G

Lanthanide complexes for drug delivery and therapeutics

Bao, G

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Publisher:: ELSEVIER
Publication Type:: Journal Article
Citation:: Journal of Luminescence, 2020, 228
Issue Date:: 2020-12-01

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Field	Value	Language
dc.contributor.author	Bao, G https://orcid.org/0000-0001-5103-5009
dc.date.accessioned	2021-03-01T02:32:52Z
dc.date.available	2021-03-01T02:32:52Z
dc.date.issued	2020-12-01
dc.identifier.citation	Journal of Luminescence, 2020, 228
dc.identifier.issn	0022-2313
dc.identifier.issn	1872-7883
dc.identifier.uri	http://hdl.handle.net/10453/146546
dc.description.abstract	© 2020 Elsevier B.V. Lanthanide complex-based medicine combining organic ligands and individual lanthanide ions is proving successful in therapeutics, especially in drug delivery, chemotherapy, and photodynamic therapy. In this review, I discuss the coordination chemistry, antenna effect, and chelating ligands of lanthanide complexes and their key features benefiting the therapeutical monitoring and performance, such as fingerprint emissions, large pseudo-Stokes’ shifts, long lifetimes, two-photon excitations and magnetic resonance responses. While illustrating their pharmaceutical applications in drug delivery, chemotherapy and photodynamic therapy, I identify the challenges and prospective opportunities in clinical translation of the lanthanide complex-based medicine.
dc.language	English
dc.publisher	ELSEVIER
dc.relation.ispartof	Journal of Luminescence
dc.relation.isbasedon	10.1016/j.jlumin.2020.117622
dc.rights	info:eu-repo/semantics/closedAccess
dc.subject	0205 Optical Physics, 0306 Physical Chemistry (incl. Structural)
dc.subject.classification	Applied Physics
dc.title	Lanthanide complexes for drug delivery and therapeutics
dc.type	Journal Article
utslib.citation.volume	228
utslib.for	0205 Optical Physics
utslib.for	0306 Physical Chemistry (incl. Structural)
pubs.organisational-group	/University of Technology Sydney/Faculty of Engineering and Information Technology
pubs.organisational-group	/University of Technology Sydney/Faculty of Engineering and Information Technology/School of Civil and Environmental Engineering
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Science
utslib.copyright.status	closed_access	*
dc.date.updated	2021-03-01T02:32:49Z
pubs.publication-status	Published
pubs.volume	228

Abstract:

© 2020 Elsevier B.V. Lanthanide complex-based medicine combining organic ligands and individual lanthanide ions is proving successful in therapeutics, especially in drug delivery, chemotherapy, and photodynamic therapy. In this review, I discuss the coordination chemistry, antenna effect, and chelating ligands of lanthanide complexes and their key features benefiting the therapeutical monitoring and performance, such as fingerprint emissions, large pseudo-Stokes’ shifts, long lifetimes, two-photon excitations and magnetic resonance responses. While illustrating their pharmaceutical applications in drug delivery, chemotherapy and photodynamic therapy, I identify the challenges and prospective opportunities in clinical translation of the lanthanide complex-based medicine.

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http://hdl.handle.net/10453/146546