Human retrosplenial theta and alpha modulation in active spatial navigation

Do, T-TN; Lin, C-T; Gramann, K

Human retrosplenial theta and alpha modulation in active spatial navigation

Do, T-TN Lin, C-T Gramann, K

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Publisher:: Cold Spring Harbor Laboratory
Publication Type:: Journal Article
Citation:: 2020, pp. 2020.12.01.406124
Issue Date:: 2020-12-02

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Field	Value	Language
dc.contributor.author	Do, T-TN
dc.contributor.author	Lin, C-T
dc.contributor.author	Gramann, K
dc.date.accessioned	2021-03-15T23:41:02Z
dc.date.available	2021-03-15T23:41:02Z
dc.date.issued	2020-12-02
dc.identifier.citation	2020, pp. 2020.12.01.406124
dc.identifier.uri	http://hdl.handle.net/10453/147187
dc.description.abstract	<jats:title>Abstract</jats:title><jats:p>Spatial navigation is a complex cognitive process based on multiple senses that are integrated and processed by a wide network of brain areas. Previous studies have revealed the retrosplenial complex (RSC) to be modulated in a task-related manner during navigation. However, these studies restricted participants’ movement to stationary setups, which might have impacted heading computations due to the absence of vestibular and proprioceptive inputs. Here, we investigated neural dynamics of RSC in an active spatial navigation task where participants actively ambulated from one location to several other points while the position of a landmark and the starting location were updated. The results revealed theta power in the RSC to be pronounced during heading changes but not during translational movements, indicating that physical rotations induce human RSC theta activity. This finding provides a potential evidence of head-direction computation in RSC in healthy humans during active spatial navigation.</jats:p>
dc.language	en
dc.publisher	Cold Spring Harbor Laboratory
dc.relation	http://purl.org/au-research/grants/arc/DP180100670
dc.relation	http://purl.org/au-research/grants/arc/DP180100656
dc.relation.hasversion	Submitted version	en
dc.relation.isbasedon	10.1101/2020.12.01.406124
dc.rights	info:eu-repo/semantics/openAccess
dc.title	Human retrosplenial theta and alpha modulation in active spatial navigation
dc.type	Journal Article
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Engineering and Information Technology
pubs.organisational-group	/University of Technology Sydney/Strength - AAII - Australian Artificial Intelligence Institute
pubs.organisational-group	/University of Technology Sydney/Faculty of Engineering and Information Technology/School of Computer Science
utslib.copyright.status	open_access	*
dc.date.updated	2021-03-15T23:40:52Z

Abstract:

AbstractSpatial navigation is a complex cognitive process based on multiple senses that are integrated and processed by a wide network of brain areas. Previous studies have revealed the retrosplenial complex (RSC) to be modulated in a task-related manner during navigation. However, these studies restricted participants’ movement to stationary setups, which might have impacted heading computations due to the absence of vestibular and proprioceptive inputs. Here, we investigated neural dynamics of RSC in an active spatial navigation task where participants actively ambulated from one location to several other points while the position of a landmark and the starting location were updated. The results revealed theta power in the RSC to be pronounced during heading changes but not during translational movements, indicating that physical rotations induce human RSC theta activity. This finding provides a potential evidence of head-direction computation in RSC in healthy humans during active spatial navigation.

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http://hdl.handle.net/10453/147187