A microRNA in a multiple-turnover RNAi enzyme complex

Amer Assoc Advancement Science
Publication Type:
Journal Article
Science, 2002, 297 (5589), pp. 2056 - 2060
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In animals, the double-stranded RNA-specific endonuclease Dicer produces two classes of functionally distinct, tiny RNAs: microRNAs ( miRNAs) and small interfering RNAs (siRNAs). miRNAs regulate mRNA translation, whereas siRNAs direct RNA destruction via
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