A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA

Amer Assoc Advancement Science
Publication Type:
Journal Article
Science, 2001, 293 (5531), pp. 834 - 838
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The 21-nucleotide small temporal RNA (stRNA) let-7 regulates developmental timing in Caenorhabditis elegans and probably in other bilateral animals. We present in vivo and in vitro evidence that in Drosophila melanogaster a developmentally regulated prec
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