Management of acute upper respiratory tract infection: the role of early intervention.

Wang, DY; Eccles, R; Bell, J; Chua, AH; Salvi, S; Schellack, N; Marks, P; Wong, YC

Management of acute upper respiratory tract infection: the role of early intervention.

Wang, DY Eccles, R Bell, J Chua, AH Salvi, S Schellack, N Marks, P Wong, YC

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Publisher:: Informa UK Limited
Publication Type:: Journal Article
Citation:: Expert review of respiratory medicine, 2021, pp. 1-7
Issue Date:: 2021-10-06

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Field	Value	Language
dc.contributor.author	Wang, DY
dc.contributor.author	Eccles, R
dc.contributor.author	Bell, J
dc.contributor.author	Chua, AH
dc.contributor.author	Salvi, S
dc.contributor.author	Schellack, N
dc.contributor.author	Marks, P
dc.contributor.author	Wong, YC
dc.date.accessioned	2021-11-11T04:35:00Z
dc.date.available	2021-11-11T04:35:00Z
dc.date.issued	2021-10-06
dc.identifier.citation	Expert review of respiratory medicine, 2021, pp. 1-7
dc.identifier.issn	1747-6348
dc.identifier.issn	1747-6356
dc.identifier.uri	http://hdl.handle.net/10453/151509
dc.description.abstract	<h4>Introduction</h4>Upper respiratory tract infection (URTI) is an illness caused by an acute infection by viruses or bacteria of the nose, sinuses, pharynx, and larynx. Most URTIs are short, mild, and self-limiting, but some can lead to serious complications, resulting in heavy social and economic burden on individuals and society.<h4>Areas covered</h4>This article presents the management guidelines and consensus established through the Delphi method during an expert roundtable conducted in November 2020 and results of a targeted literature review.<h4>Expert opinion</h4>There is currently no available cure for acute URTI and management strategies aim towards symptom alleviation and prevention of URTI virus transmission. The effectiveness of these strategies is highly increased with early intervention, administered prior to the peaking of viral shedding. This reduces the chances of developing a full-blown acute URTI, decreases symptom severity, and reduces viral transmission. Mucoadhesive gel nasal sprays have shown promising results for early intervention of acute URTI. They act by creating a barrier that can trap virus particles, thereby preventing invasion of the mucosa by the virus. Additionally, they deliver broad spectrum activity that is effective against a wide variety of pathogens that cause acute URTI. Acute URTI warrants greater attention and proactive management in reducing its burden.
dc.format	Print-Electronic
dc.language	eng
dc.publisher	Informa UK Limited
dc.relation.ispartof	Expert review of respiratory medicine
dc.relation.isbasedon	10.1080/17476348.2021.1988569
dc.rights	info:eu-repo/semantics/closedAccess
dc.subject	1117 Public Health and Health Services
dc.subject.classification	Respiratory System
dc.title	Management of acute upper respiratory tract infection: the role of early intervention.
dc.type	Journal Article
utslib.location.activity	England
utslib.for	1117 Public Health and Health Services
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Health
pubs.organisational-group	/University of Technology Sydney/Faculty of Health/Graduate School of Health
pubs.organisational-group	/University of Technology Sydney/Faculty of Health/Graduate School of Health/GSH.Pharmacy
utslib.copyright.status	closed_access	*
dc.date.updated	2021-11-11T04:34:59Z
pubs.publication-status	Published

Abstract:

Introduction

Upper respiratory tract infection (URTI) is an illness caused by an acute infection by viruses or bacteria of the nose, sinuses, pharynx, and larynx. Most URTIs are short, mild, and self-limiting, but some can lead to serious complications, resulting in heavy social and economic burden on individuals and society.

Areas covered

This article presents the management guidelines and consensus established through the Delphi method during an expert roundtable conducted in November 2020 and results of a targeted literature review.

Expert opinion

There is currently no available cure for acute URTI and management strategies aim towards symptom alleviation and prevention of URTI virus transmission. The effectiveness of these strategies is highly increased with early intervention, administered prior to the peaking of viral shedding. This reduces the chances of developing a full-blown acute URTI, decreases symptom severity, and reduces viral transmission. Mucoadhesive gel nasal sprays have shown promising results for early intervention of acute URTI. They act by creating a barrier that can trap virus particles, thereby preventing invasion of the mucosa by the virus. Additionally, they deliver broad spectrum activity that is effective against a wide variety of pathogens that cause acute URTI. Acute URTI warrants greater attention and proactive management in reducing its burden.

Please use this identifier to cite or link to this item:

http://hdl.handle.net/10453/151509