Recent Advances in Chronotherapy Targeting Respiratory Diseases

Paudel, KR; Jha, SK; Allam, VSRR; Prasher, P; Gupta, PK; Bhattacharjee, R; Jha, NK; Vishwas, S; Singh, SK; Shrestha, J; Imran, M; Panth, N; Chellappan, DK; Ebrahimi Warkiani, M; Hansbro, PM; Dua, K

Recent Advances in Chronotherapy Targeting Respiratory Diseases

Paudel, KR Jha, SK Allam, VSRR Prasher, P Gupta, PK Bhattacharjee, R Jha, NK Vishwas, S Singh, SK Shrestha, J Imran, M Panth, N Chellappan, DK Ebrahimi Warkiani, M Hansbro, PM Dua, K

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Publisher:: MDPI AG
Publication Type:: Journal Article
Citation:: Pharmaceutics, 13, (12), pp. 2008-2008

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Field	Value	Language
dc.contributor.author	Paudel, KR
dc.contributor.author	Jha, SK
dc.contributor.author	Allam, VSRR
dc.contributor.author	Prasher, P
dc.contributor.author	Gupta, PK
dc.contributor.author	Bhattacharjee, R
dc.contributor.author	Jha, NK
dc.contributor.author	Vishwas, S
dc.contributor.author	Singh, SK
dc.contributor.author	Shrestha, J
dc.contributor.author	Imran, M
dc.contributor.author	Panth, N
dc.contributor.author	Chellappan, DK
dc.contributor.author	Ebrahimi Warkiani, M
dc.contributor.author	Hansbro, PM
dc.contributor.author	Dua, K https://orcid.org/0000-0002-7507-1159
dc.date.accessioned	2021-12-01T06:33:20Z
dc.date.available	2021-12-01T06:33:20Z
dc.identifier.citation	Pharmaceutics, 13, (12), pp. 2008-2008
dc.identifier.issn	1999-4923
dc.identifier.uri	http://hdl.handle.net/10453/151991
dc.description.abstract	<jats:p>Respiratory diseases contribute to a significant percentage of mortality and morbidity worldwide. The circadian rhythm is a natural biological process where our bodily functions align with the 24 h oscillation (sleep–wake cycle) process and are controlled by the circadian clock protein/gene. Disruption of the circadian rhythm could alter normal lung function. Chronotherapy is a type of therapy provided at specific time intervals based on an individual’s circadian rhythm. This would allow the drug to show optimum action, and thereby modulate its pharmacokinetics to lessen unwanted or unintended effects. In this review, we deliberated on the recent advances employed in chrono-targeted therapeutics for chronic respiratory diseases.</jats:p>
dc.language	en
dc.publisher	MDPI AG
dc.relation.ispartof	Pharmaceutics
dc.relation.isbasedon	10.3390/pharmaceutics13122008
dc.rights	info:eu-repo/semantics/openAccess
dc.subject	1115 Pharmacology and Pharmaceutical Sciences
dc.title	Recent Advances in Chronotherapy Targeting Respiratory Diseases
dc.type	Journal Article
utslib.citation.volume	13
utslib.for	1115 Pharmacology and Pharmaceutical Sciences
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Health
pubs.organisational-group	/University of Technology Sydney/Faculty of Science
pubs.organisational-group	/University of Technology Sydney/Faculty of Health/Graduate School of Health
pubs.organisational-group	/University of Technology Sydney/Faculty of Health/Graduate School of Health/GSH.Pharmacy
utslib.copyright.status	open_access	*
dc.date.updated	2021-12-01T06:33:19Z
pubs.issue	12
pubs.publication-status	Published online
pubs.volume	13
utslib.citation.issue	12

Abstract:

Respiratory diseases contribute to a significant percentage of mortality and morbidity worldwide. The circadian rhythm is a natural biological process where our bodily functions align with the 24 h oscillation (sleep–wake cycle) process and are controlled by the circadian clock protein/gene. Disruption of the circadian rhythm could alter normal lung function. Chronotherapy is a type of therapy provided at specific time intervals based on an individual’s circadian rhythm. This would allow the drug to show optimum action, and thereby modulate its pharmacokinetics to lessen unwanted or unintended effects. In this review, we deliberated on the recent advances employed in chrono-targeted therapeutics for chronic respiratory diseases.

Please use this identifier to cite or link to this item:

http://hdl.handle.net/10453/151991