Tea (Catechins Including (−)-Epigallocatechin-3-gallate) and Cancer

Devkota, HP; Adhikari-Devkota, A; Paudel, KR; Panth, N; Chellappan, DK; Hansbro, P; Dua, K

Tea (Catechins Including (−)-Epigallocatechin-3-gallate) and Cancer

Devkota, HP Adhikari-Devkota, A Paudel, KR Panth, N Chellappan, DK Hansbro, P

Dua, K

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Publisher:: Springer
Publication Type:: Chapter
Citation:: Nutraceuticals and Cancer Signaling Clinical Aspects and Mode of Action, 2021, pp. 451-466
Issue Date:: 2021-09-25

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Field	Value	Language
dc.contributor.author	Devkota, HP
dc.contributor.author	Adhikari-Devkota, A
dc.contributor.author	Paudel, KR
dc.contributor.author	Panth, N
dc.contributor.author	Chellappan, DK
dc.contributor.author	Hansbro, P https://orcid.org/0000-0002-4741-3035
dc.contributor.author	Dua, K https://orcid.org/0000-0002-7507-1159
dc.contributor.editor	Jafari, SM
dc.contributor.editor	Nabavi, SM
dc.contributor.editor	Silva, AS
dc.date.accessioned	2022-01-10T22:10:44Z
dc.date.available	2022-01-10T22:10:44Z
dc.date.issued	2021-09-25
dc.identifier.citation	Nutraceuticals and Cancer Signaling Clinical Aspects and Mode of Action, 2021, pp. 451-466
dc.identifier.isbn	303074034X
dc.identifier.isbn	9783030740344
dc.identifier.uri	http://hdl.handle.net/10453/152881
dc.description.abstract	Catechins, a group of phenolic compounds (flavan-3-ols), are one of most widely studied plant secondary metabolites regarding their diverse pharmacological actions. Found in many foods and beverages including tea, catechins are reported to be useful for the prevention and treatment of cancer in in vitro and in vivo studies. Various signalling mechanisms have also been explored for the cancer chemopreventive activities of tea and tea catechins. However, the translational research on these compounds to clinical studies have not been performed in detail as compared to in vitro and in vivo studies. This chapter critically discusses the role of catechins in cancer prevention and treatment with special focus on their mechanism of action on signaling pathways.
dc.format.extent	22
dc.language	en
dc.publisher	Springer
dc.relation.ispartof	Nutraceuticals and Cancer Signaling Clinical Aspects and Mode of Action
dc.relation.isbasedon	10.1007/978-3-030-74035-1_17
dc.rights	info:eu-repo/semantics/closedAccess
dc.title	Tea (Catechins Including (−)-Epigallocatechin-3-gallate) and Cancer
dc.type	Chapter
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Health
pubs.organisational-group	/University of Technology Sydney/Faculty of Science
pubs.organisational-group	/University of Technology Sydney/Faculty of Science/School of Life Sciences
pubs.organisational-group	/University of Technology Sydney/Faculty of Health/Graduate School of Health
pubs.organisational-group	/University of Technology Sydney/Faculty of Health/Graduate School of Health/GSH.Pharmacy
utslib.copyright.status	closed_access	*
pubs.consider-herdc	false
dc.date.updated	2022-01-10T22:10:43Z
pubs.publication-status	Published

Abstract:

Catechins, a group of phenolic compounds (flavan-3-ols), are one of most widely studied plant secondary metabolites regarding their diverse pharmacological actions. Found in many foods and beverages including tea, catechins are reported to be useful for the prevention and treatment of cancer in in vitro and in vivo studies. Various signalling mechanisms have also been explored for the cancer chemopreventive activities of tea and tea catechins. However, the translational research on these compounds to clinical studies have not been performed in detail as compared to in vitro and in vivo studies. This chapter critically discusses the role of catechins in cancer prevention and treatment with special focus on their mechanism of action on signaling pathways.

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http://hdl.handle.net/10453/152881