Synthesis and characterization of PCU@C-Ag/AgCl nanoparticles as an antimicrobial material for respiratory tract infection

Palanisamy, S; Subramanian, K; Bennet, LG; Ambrose, J; Gopalakrishnan, A; Babu, S; Rajamani, R; Jha, NK; Pandit, S; Singh, SK; Dua, K; Gupta, PK

Synthesis and characterization of PCU@C-Ag/AgCl nanoparticles as an antimicrobial material for respiratory tract infection

Palanisamy, S Subramanian, K Bennet, LG Ambrose, J Gopalakrishnan, A Babu, S Rajamani, R Jha, NK Pandit, S Singh, SK Dua, K

Gupta, PK

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Publisher:: Walter de Gruyter GmbH
Publication Type:: Journal Article
Citation:: Nanofabrication, 2021, 6, (1), pp. 68-78
Issue Date:: 2021-01-01

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Field	Value	Language
dc.contributor.author	Palanisamy, S
dc.contributor.author	Subramanian, K
dc.contributor.author	Bennet, LG
dc.contributor.author	Ambrose, J
dc.contributor.author	Gopalakrishnan, A
dc.contributor.author	Babu, S
dc.contributor.author	Rajamani, R
dc.contributor.author	Jha, NK
dc.contributor.author	Pandit, S
dc.contributor.author	Singh, SK
dc.contributor.author	Dua, K https://orcid.org/0000-0002-7507-1159
dc.contributor.author	Gupta, PK
dc.date.accessioned	2022-01-11T22:23:35Z
dc.date.available	2022-01-11T22:23:35Z
dc.date.issued	2021-01-01
dc.identifier.citation	Nanofabrication, 2021, 6, (1), pp. 68-78
dc.identifier.issn	2299-680X
dc.identifier.uri	http://hdl.handle.net/10453/152935
dc.description.abstract	<jats:title>Abstract</jats:title> <jats:p>The pregnant cow urine (PCU) is an active source of antimicrobial agents that is used for fabricating chitosan coated Ag/AgCl nanoparticles (NPs) in the present study. These PCU@C-Ag/AgCl NPs were physicochemically characterized and evaluated for antimicrobial activity against selected respiratory tract infection (RTI) pathogens. The absorption band around 420 nm in UV-Visible spectrum indicated the presence of Ag NPs. The spherical shape of NPs was observed using TEM. Also, the crystalline structure was confirmed using the XRD pattern. The PCU@C-Ag/AgCl NPs showed strong antimicrobial activity against all tested RTI pathogens. In addition, FESEM analysis showed morphological changes in RTI bacterial pathogens. Thereby, PCU@C-Ag/AgCl NPs may be used as an antimicrobial material to treat RTIs in near future at clinical level.</jats:p>
dc.language	en
dc.publisher	Walter de Gruyter GmbH
dc.relation.ispartof	Nanofabrication
dc.relation.isbasedon	10.1515/nanofab-2020-0106
dc.rights	info:eu-repo/semantics/openAccess
dc.rights	Open Access. © 2021 S. Palanisamy et al., published by De Gruyter. This work is licensed under the Creative Commons Attribution 4.0 License
dc.title	Synthesis and characterization of PCU@C-Ag/AgCl nanoparticles as an antimicrobial material for respiratory tract infection
dc.type	Journal Article
utslib.citation.volume	6
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Health
pubs.organisational-group	/University of Technology Sydney/Faculty of Health/Graduate School of Health
pubs.organisational-group	/University of Technology Sydney/Faculty of Health/Graduate School of Health/GSH.Pharmacy
utslib.copyright.status	open_access	*
dc.date.updated	2022-01-11T22:23:33Z
pubs.issue	1
pubs.publication-status	Published
pubs.volume	6
utslib.citation.issue	1

Abstract:

Abstract The pregnant cow urine (PCU) is an active source of antimicrobial agents that is used for fabricating chitosan coated Ag/AgCl nanoparticles (NPs) in the present study. These PCU@C-Ag/AgCl NPs were physicochemically characterized and evaluated for antimicrobial activity against selected respiratory tract infection (RTI) pathogens. The absorption band around 420 nm in UV-Visible spectrum indicated the presence of Ag NPs. The spherical shape of NPs was observed using TEM. Also, the crystalline structure was confirmed using the XRD pattern. The PCU@C-Ag/AgCl NPs showed strong antimicrobial activity against all tested RTI pathogens. In addition, FESEM analysis showed morphological changes in RTI bacterial pathogens. Thereby, PCU@C-Ag/AgCl NPs may be used as an antimicrobial material to treat RTIs in near future at clinical level.

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http://hdl.handle.net/10453/152935