Human brain dynamics in active spatial navigation

Do, T-TN; Lin, C-T; Gramann, K

Human brain dynamics in active spatial navigation

Do, T-TN Lin, C-T Gramann, K

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Publisher:: NATURE RESEARCH
Publication Type:: Journal Article
Citation:: Scientific Reports, 2021, 11, (1), pp. 13036
Issue Date:: 2021-06-22

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Field	Value	Language
dc.contributor.author	Do, T-TN
dc.contributor.author	Lin, C-T
dc.contributor.author	Gramann, K
dc.date.accessioned	2022-04-01T02:26:03Z
dc.date.available	2021-06-08
dc.date.available	2022-04-01T02:26:03Z
dc.date.issued	2021-06-22
dc.identifier.citation	Scientific Reports, 2021, 11, (1), pp. 13036
dc.identifier.issn	2045-2322
dc.identifier.issn	2045-2322
dc.identifier.uri	http://hdl.handle.net/10453/155849
dc.description.abstract	Spatial navigation is a complex cognitive process based on multiple senses that are integrated and processed by a wide network of brain areas. Previous studies have revealed the retrosplenial complex (RSC) to be modulated in a task-related manner during navigation. However, these studies restricted participants' movement to stationary setups, which might have impacted heading computations due to the absence of vestibular and proprioceptive inputs. Here, we present evidence of human RSC theta oscillation (4-8 Hz) in an active spatial navigation task where participants actively ambulated from one location to several other points while the position of a landmark and the starting location were updated. The results revealed theta power in the RSC to be pronounced during heading changes but not during translational movements, indicating that physical rotations induce human RSC theta activity. This finding provides a potential evidence of head-direction computation in RSC in healthy humans during active spatial navigation.
dc.format	Electronic
dc.language	eng
dc.publisher	NATURE RESEARCH
dc.relation	http://purl.org/au-research/grants/arc/DP180100670
dc.relation	http://purl.org/au-research/grants/arc/DP180100656
dc.relation.ispartof	Scientific Reports
dc.relation.isbasedon	10.1038/s41598-021-92246-4
dc.rights	info:eu-repo/semantics/closedAccess
dc.subject.mesh	Adult
dc.subject.mesh	Behavior
dc.subject.mesh	Brain
dc.subject.mesh	Electroencephalography
dc.subject.mesh	Evoked Potentials
dc.subject.mesh	Female
dc.subject.mesh	Gyrus Cinguli
dc.subject.mesh	Humans
dc.subject.mesh	Male
dc.subject.mesh	Nerve Net
dc.subject.mesh	Spatial Navigation
dc.subject.mesh	Brain
dc.subject.mesh	Gyrus Cinguli
dc.subject.mesh	Nerve Net
dc.subject.mesh	Humans
dc.subject.mesh	Electroencephalography
dc.subject.mesh	Behavior
dc.subject.mesh	Evoked Potentials
dc.subject.mesh	Adult
dc.subject.mesh	Female
dc.subject.mesh	Male
dc.subject.mesh	Spatial Navigation
dc.title	Human brain dynamics in active spatial navigation
dc.type	Journal Article
utslib.citation.volume	11
utslib.location.activity	England
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Engineering and Information Technology
pubs.organisational-group	/University of Technology Sydney/Strength - AAII - Australian Artificial Intelligence Institute
pubs.organisational-group	/University of Technology Sydney/Faculty of Engineering and Information Technology/School of Computer Science
utslib.copyright.status	closed_access	*
dc.date.updated	2022-04-01T02:25:32Z
pubs.issue	1
pubs.publication-status	Published online
pubs.volume	11
utslib.citation.issue	1

Abstract:

Spatial navigation is a complex cognitive process based on multiple senses that are integrated and processed by a wide network of brain areas. Previous studies have revealed the retrosplenial complex (RSC) to be modulated in a task-related manner during navigation. However, these studies restricted participants' movement to stationary setups, which might have impacted heading computations due to the absence of vestibular and proprioceptive inputs. Here, we present evidence of human RSC theta oscillation (4-8 Hz) in an active spatial navigation task where participants actively ambulated from one location to several other points while the position of a landmark and the starting location were updated. The results revealed theta power in the RSC to be pronounced during heading changes but not during translational movements, indicating that physical rotations induce human RSC theta activity. This finding provides a potential evidence of head-direction computation in RSC in healthy humans during active spatial navigation.

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http://hdl.handle.net/10453/155849