Implementation of forward osmosis to concentrate alpha-ketoglutaric acid from fermentation broth: Performance and fouling analysis

Szczygiełda, M; Krajewska, M; Zheng, L; Nghiem, LD; Prochaska, K

Implementation of forward osmosis to concentrate alpha-ketoglutaric acid from fermentation broth: Performance and fouling analysis

Szczygiełda, M Krajewska, M Zheng, L Nghiem, LD Prochaska, K

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Publisher:: ELSEVIER
Publication Type:: Journal Article
Citation:: Journal of Membrane Science, 2021, 637
Issue Date:: 2021-11-01

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Field	Value	Language
dc.contributor.author	Szczygiełda, M
dc.contributor.author	Krajewska, M
dc.contributor.author	Zheng, L
dc.contributor.author	Nghiem, LD
dc.contributor.author	Prochaska, K
dc.date.accessioned	2022-05-04T21:49:32Z
dc.date.available	2022-05-04T21:49:32Z
dc.date.issued	2021-11-01
dc.identifier.citation	Journal of Membrane Science, 2021, 637
dc.identifier.issn	0376-7388
dc.identifier.issn	1873-3123
dc.identifier.uri	http://hdl.handle.net/10453/157015
dc.description.abstract	Forward osmosis (FO) was demonstrated as a promising method to concentrate alpha-ketoglutaric acid in fermentation broth. Using a model solution containing alpha-ketoglutaric acid, the impact of the initial pH value on water flux, reverse salt flux, and rejection of alpha-ketoglutaric acid were first elucidated. Results from this study show that water flux was not affected by feed solution pH. However, feed solution pH could influence alpha-ketoglutaric acid rejection and reverse salt flux. The highest alpha-ketoglutaric acid rejection of 99.7% and lowest reverse salt flux were observed at pH 5. Multi-component model and real fermentation broth were then used to validate FO application for concentrating alpha-ketoglutaric acid. Water recovery of 80% was achieved without severe membrane fouling. In addition, membrane fouling analysis show that the built-up fouling layer of impurities is flaky and of unstable nature, suggesting that membrane fouling could be reversible. Knowledge of the fouling layer formation can contribute to the development of an effective method of pretreatment of the fermentation broth and cleaning FO membranes in the future.
dc.language	English
dc.publisher	ELSEVIER
dc.relation.ispartof	Journal of Membrane Science
dc.relation.isbasedon	10.1016/j.memsci.2021.119593
dc.rights	info:eu-repo/semantics/embargoedAccess
dc.subject	03 Chemical Sciences, 09 Engineering
dc.subject.classification	Chemical Engineering
dc.title	Implementation of forward osmosis to concentrate alpha-ketoglutaric acid from fermentation broth: Performance and fouling analysis
dc.type	Journal Article
utslib.citation.volume	637
utslib.for	03 Chemical Sciences
utslib.for	09 Engineering
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Engineering and Information Technology
pubs.organisational-group	/University of Technology Sydney/Faculty of Engineering and Information Technology/School of Civil and Environmental Engineering
pubs.organisational-group	/University of Technology Sydney/Strength - CTWW - Centre for Technology in Water and Wastewater Treatment
utslib.copyright.status	open_access	*
utslib.copyright.embargo	2023-11-01T00:00:00+1000Z
dc.date.updated	2022-05-04T21:49:29Z
pubs.publication-status	Published
pubs.volume	637

Abstract:

Forward osmosis (FO) was demonstrated as a promising method to concentrate alpha-ketoglutaric acid in fermentation broth. Using a model solution containing alpha-ketoglutaric acid, the impact of the initial pH value on water flux, reverse salt flux, and rejection of alpha-ketoglutaric acid were first elucidated. Results from this study show that water flux was not affected by feed solution pH. However, feed solution pH could influence alpha-ketoglutaric acid rejection and reverse salt flux. The highest alpha-ketoglutaric acid rejection of 99.7% and lowest reverse salt flux were observed at pH 5. Multi-component model and real fermentation broth were then used to validate FO application for concentrating alpha-ketoglutaric acid. Water recovery of 80% was achieved without severe membrane fouling. In addition, membrane fouling analysis show that the built-up fouling layer of impurities is flaky and of unstable nature, suggesting that membrane fouling could be reversible. Knowledge of the fouling layer formation can contribute to the development of an effective method of pretreatment of the fermentation broth and cleaning FO membranes in the future.

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http://hdl.handle.net/10453/157015