Combining Support Vector Machines and the t-statistic for Gene Selection in DNA Microarray Data Analysis

Publisher:
Springer Berlin / Heidelberg
Publication Type:
Conference Proceeding
Citation:
Advances in Knowledge Discovery and Data Mining - Lecture Notes in Artificial Intelligence, 2010, 6119 pp. 55 - 62
Issue Date:
2010-01
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This paper proposes a new gene selection (or feature selection) method for DNA microarray data analysis. In the method, the t-statistic and support vector machines are combined efficiently. The resulting gene selection method uses both the data intrinsic information and learning algorithm performance to measure the relevance of a gene in a DNA microarray. We explain why and how the proposed method works well. The experimental results on two benchmarking microarray data sets show that the proposed method is competitive with previous methods. The proposed method can also be used for other feature selection problems.
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