Genetic algorithm based fuzzy multiple regression for the nocturnal hypoglycaemia detection

Publication Type:
Conference Proceeding
2010 IEEE World Congress on Computational Intelligence, WCCI 2010 - 2010 IEEE Congress on Evolutionary Computation, CEC 2010, 2010
Issue Date:
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Low blood glucose (Hypoglycaemia) is dangerous and can result in unconsciousness, seizures and even death. It has a common and serious side effect of insulin therapy in patients with diabetes. We measure physiological parameters (heart rate, corrected QT interval of the electrocardiogram (ECG) signal, change of heart rate, and the change of corrected QT interval) continuously to provide detection of hypoglycaemic. Based on these physiological parameters, we have developed a genetic algorithm based multiple regression model to determine the presence of hypoglycaemic episodes. Genetic algorithm is used to determine the optimal parameters of the multiple regression. The overall data were organized into a training set (8 patients) and a testing set (another 8 patient) which are randomly selected. The clinical results show that the proposed algorithm can achieve predictions with good sensitivities and acceptable specificities. © 2010 IEEE.
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