Cost-effectiveness of clinical interventions for delirium: A systematic literature review of economic evaluations.

Kinchin, I; Edwards, L; Hosie, A; Agar, M; Mitchell, E; Trepel, D

Cost-effectiveness of clinical interventions for delirium: A systematic literature review of economic evaluations.

Kinchin, I

Edwards, L Hosie, A

Agar, M

Mitchell, E Trepel, D

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Publisher:: WILEY
Publication Type:: Journal Article
Citation:: Acta Psychiatr Scand, 2022
Issue Date:: 2022-05-20

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Field	Value	Language
dc.contributor.author	Kinchin, I https://orcid.org/0000-0003-0133-2763
dc.contributor.author	Edwards, L
dc.contributor.author	Hosie, A https://orcid.org/0000-0003-1674-2124
dc.contributor.author	Agar, M https://orcid.org/0000-0002-6756-6119
dc.contributor.author	Mitchell, E
dc.contributor.author	Trepel, D
dc.date.accessioned	2022-11-30T02:41:14Z
dc.date.available	2022-05-17
dc.date.available	2022-11-30T02:41:14Z
dc.date.issued	2022-05-20
dc.identifier.citation	Acta Psychiatr Scand, 2022
dc.identifier.issn	0001-690X
dc.identifier.issn	1600-0447
dc.identifier.uri	http://hdl.handle.net/10453/163873
dc.description.abstract	OBJECTIVE: Little is known about the economic value of clinical interventions for delirium. This review aims to synthesise and appraise available economic evidence, including resource use, costs, and cost-effectiveness of interventions for reducing, preventing, and treating delirium. METHODS: Systematic review of published and grey literature on full and partial economic evaluations. Study quality was assessed using the Consolidated Health Economic Evaluation Reporting Standards (CHEERS). RESULTS: Fourteen economic evaluations (43% full, 57% partial) across nine multicomponent and nonpharmacological intervention types met inclusion criteria. The intervention costs ranged between US$386 and $553 per person in inpatient settings. Multicomponent delirium prevention intervention and the Hospital Elder Life Program (HELP) reported statistically significant cost savings or cost offsets somewhere else in the health system. Cost savings related to inpatient, outpatient, and out-of-pocket costs ranged between $194 and $6022 per person. The average CHEERS score was 74% (±SD 10%). CONCLUSION: Evidence on a joint distribution of costs and outcomes of delirium interventions was limited, varied and of generally low quality. Directed expansion of health economics towards the evaluation of delirium care is necessary to ensure effective implementation that meets patients' needs and is cost-effective in achieving similar or better outcomes for the same or lower cost.
dc.format	Print-Electronic
dc.language	eng
dc.publisher	WILEY
dc.relation.ispartof	Acta Psychiatr Scand
dc.relation.isbasedon	10.1111/acps.13457
dc.rights	info:eu-repo/semantics/openAccess
dc.subject	11 Medical and Health Sciences, 17 Psychology and Cognitive Sciences
dc.subject.classification	Psychiatry
dc.title	Cost-effectiveness of clinical interventions for delirium: A systematic literature review of economic evaluations.
dc.type	Journal Article
utslib.location.activity	United States
utslib.for	11 Medical and Health Sciences
utslib.for	17 Psychology and Cognitive Sciences
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Health
pubs.organisational-group	/University of Technology Sydney/Strength - CHERE - Centre for Health Economics Research and Evaluation
pubs.organisational-group	/University of Technology Sydney/Faculty of Health/IMPACCT
utslib.copyright.status	open_access	*
dc.date.updated	2022-11-30T02:41:12Z
pubs.publication-status	Published online

Abstract:

OBJECTIVE: Little is known about the economic value of clinical interventions for delirium. This review aims to synthesise and appraise available economic evidence, including resource use, costs, and cost-effectiveness of interventions for reducing, preventing, and treating delirium. METHODS: Systematic review of published and grey literature on full and partial economic evaluations. Study quality was assessed using the Consolidated Health Economic Evaluation Reporting Standards (CHEERS). RESULTS: Fourteen economic evaluations (43% full, 57% partial) across nine multicomponent and nonpharmacological intervention types met inclusion criteria. The intervention costs ranged between US$386 and $553 per person in inpatient settings. Multicomponent delirium prevention intervention and the Hospital Elder Life Program (HELP) reported statistically significant cost savings or cost offsets somewhere else in the health system. Cost savings related to inpatient, outpatient, and out-of-pocket costs ranged between $194 and $6022 per person. The average CHEERS score was 74% (±SD 10%). CONCLUSION: Evidence on a joint distribution of costs and outcomes of delirium interventions was limited, varied and of generally low quality. Directed expansion of health economics towards the evaluation of delirium care is necessary to ensure effective implementation that meets patients' needs and is cost-effective in achieving similar or better outcomes for the same or lower cost.

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http://hdl.handle.net/10453/163873