Comparison of six frailty instruments in adults with heart failure: a prospective cohort pilot study.

McDonagh, J; Ferguson, C; Prichard, R; Chang, S; Philips, JL; Davidson, PM; Newton, PJ; Macdonald, PS

Comparison of six frailty instruments in adults with heart failure: a prospective cohort pilot study.

McDonagh, J Ferguson, C Prichard, R

Chang, S

Philips, JL Davidson, PM Newton, PJ Macdonald, PS

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Publisher:: Oxford University Press (OUP)
Publication Type:: Journal Article
Citation:: Eur J Cardiovasc Nurs, 2022, pp. zvac100
Issue Date:: 2022-10-27

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Field	Value	Language
dc.contributor.author	McDonagh, J
dc.contributor.author	Ferguson, C
dc.contributor.author	Prichard, R https://orcid.org/0000-0001-8057-6605
dc.contributor.author	Chang, S https://orcid.org/0000-0003-0723-3192
dc.contributor.author	Philips, JL
dc.contributor.author	Davidson, PM
dc.contributor.author	Newton, PJ
dc.contributor.author	Macdonald, PS
dc.date.accessioned	2022-12-02T02:11:15Z
dc.date.available	2022-10-21
dc.date.available	2022-12-02T02:11:15Z
dc.date.issued	2022-10-27
dc.identifier.citation	Eur J Cardiovasc Nurs, 2022, pp. zvac100
dc.identifier.issn	1474-5151
dc.identifier.issn	1873-1953
dc.identifier.uri	http://hdl.handle.net/10453/164052
dc.description.abstract	AIM: To compare the frailty prevalence and predictive performance of six frailty instruments in adults with heart failure and determine feasibility of study methods. METHODS AND RESULTS: Prospective cohort pilot study. Adults aged 18 years or older with a confirmed diagnosis of heart failure in Sydney, New South Wales, Australia. The Frailty Phenotype; the Survey of Health, Ageing and Retirement in Europe Frailty Instrument (SHARE-FI); St Vincent's Frailty instrument; St Vincent's Frailty instrument plus cognition and mood; The Fatigue, Resistance, Ambulation, Illnesses, and Loss of Weight (FRAIL) scale; and the Deficit Accumulation Index were compared. Multiple logistic regression was used to develop six frailty instrument models to evaluate the association between each frailty instrument and composite all-cause rehospitalisation and mortality at 12 monthsOne hundred and thirty-one patients were included with a mean age of 54 (± 14[SD]). Frailty prevalence ranged from 33-81%. All instruments except one (the FRAIL scale) appeared to signal an increased odds of rehospitalisation and/or mortality, yet these results were non-significant. The six frailty instrument models displayed sensitivity between 88-92% and C-statistic values of 0.71-0.73, suggesting satisfactory discrimination. CONCLUSIONS: The prevalence of frailty varied across six frailty instruments yet was in the higher range despite a 'younger' heart failure cohort. Further research is required to confirm the psychometric properties of these instruments for routine clinical use in an adequately powered and more diverse heart failure cohort.
dc.format	Print-Electronic
dc.language	eng
dc.publisher	Oxford University Press (OUP)
dc.relation.ispartof	Eur J Cardiovasc Nurs
dc.relation.isbasedon	10.1093/eurjcn/zvac100
dc.rights	info:eu-repo/semantics/openAccess
dc.subject	1102 Cardiorespiratory Medicine and Haematology, 1110 Nursing, 1117 Public Health and Health Services
dc.subject.classification	Nursing
dc.title	Comparison of six frailty instruments in adults with heart failure: a prospective cohort pilot study.
dc.type	Journal Article
utslib.location.activity	England
utslib.for	1102 Cardiorespiratory Medicine and Haematology
utslib.for	1110 Nursing
utslib.for	1117 Public Health and Health Services
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Health
pubs.organisational-group	/University of Technology Sydney/Strength - CHSP - Health Services and Practice
pubs.organisational-group	/University of Technology Sydney/Faculty of Health/IMPACCT
pubs.organisational-group	/University of Technology Sydney/Faculty of Health/Public Health
utslib.copyright.status	open_access	*
dc.date.updated	2022-12-02T02:11:12Z
pubs.publication-status	Published online

Abstract:

AIM: To compare the frailty prevalence and predictive performance of six frailty instruments in adults with heart failure and determine feasibility of study methods. METHODS AND RESULTS: Prospective cohort pilot study. Adults aged 18 years or older with a confirmed diagnosis of heart failure in Sydney, New South Wales, Australia. The Frailty Phenotype; the Survey of Health, Ageing and Retirement in Europe Frailty Instrument (SHARE-FI); St Vincent's Frailty instrument; St Vincent's Frailty instrument plus cognition and mood; The Fatigue, Resistance, Ambulation, Illnesses, and Loss of Weight (FRAIL) scale; and the Deficit Accumulation Index were compared. Multiple logistic regression was used to develop six frailty instrument models to evaluate the association between each frailty instrument and composite all-cause rehospitalisation and mortality at 12 monthsOne hundred and thirty-one patients were included with a mean age of 54 (± 14[SD]). Frailty prevalence ranged from 33-81%. All instruments except one (the FRAIL scale) appeared to signal an increased odds of rehospitalisation and/or mortality, yet these results were non-significant. The six frailty instrument models displayed sensitivity between 88-92% and C-statistic values of 0.71-0.73, suggesting satisfactory discrimination. CONCLUSIONS: The prevalence of frailty varied across six frailty instruments yet was in the higher range despite a 'younger' heart failure cohort. Further research is required to confirm the psychometric properties of these instruments for routine clinical use in an adequately powered and more diverse heart failure cohort.

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http://hdl.handle.net/10453/164052