1000 spider silkomes: Linking sequences to silk physical properties.
Arakawa, K
Kono, N
Malay, AD
Tateishi, A
Ifuku, N
Masunaga, H
Sato, R
Tsuchiya, K
Ohtoshi, R
Pedrazzoli, D
Shinohara, A
Ito, Y
Nakamura, H
Tanikawa, A
Suzuki, Y
Ichikawa, T
Fujita, S
Fujiwara, M
Tomita, M
Blamires, SJ
Chuah, J-A
Craig, H
Foong, CP
Greco, G
Guan, J
Holland, C
Kaplan, DL
Sudesh, K
Mandal, BB
Norma-Rashid, Y
Oktaviani, NA
Preda, RC
Pugno, NM
Rajkhowa, R
Wang, X
Yazawa, K
Zheng, Z
Numata, K
- Publisher:
- American Association for the Advancement of Science (AAAS)
- Publication Type:
- Journal Article
- Citation:
- Sci Adv, 2022, 8, (41), pp. eabo6043
- Issue Date:
- 2022-10-14
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Full metadata record
| Field | Value | Language |
|---|---|---|
| dc.contributor.author | Arakawa, K | |
| dc.contributor.author | Kono, N | |
| dc.contributor.author | Malay, AD | |
| dc.contributor.author | Tateishi, A | |
| dc.contributor.author | Ifuku, N | |
| dc.contributor.author | Masunaga, H | |
| dc.contributor.author | Sato, R | |
| dc.contributor.author | Tsuchiya, K | |
| dc.contributor.author | Ohtoshi, R | |
| dc.contributor.author | Pedrazzoli, D | |
| dc.contributor.author | Shinohara, A | |
| dc.contributor.author | Ito, Y | |
| dc.contributor.author | Nakamura, H | |
| dc.contributor.author | Tanikawa, A | |
| dc.contributor.author | Suzuki, Y | |
| dc.contributor.author | Ichikawa, T | |
| dc.contributor.author | Fujita, S | |
| dc.contributor.author | Fujiwara, M | |
| dc.contributor.author | Tomita, M | |
| dc.contributor.author | Blamires, SJ | |
| dc.contributor.author | Chuah, J-A | |
| dc.contributor.author | Craig, H | |
| dc.contributor.author | Foong, CP | |
| dc.contributor.author | Greco, G | |
| dc.contributor.author | Guan, J | |
| dc.contributor.author | Holland, C | |
| dc.contributor.author | Kaplan, DL | |
| dc.contributor.author | Sudesh, K | |
| dc.contributor.author | Mandal, BB | |
| dc.contributor.author | Norma-Rashid, Y | |
| dc.contributor.author | Oktaviani, NA | |
| dc.contributor.author | Preda, RC | |
| dc.contributor.author | Pugno, NM | |
| dc.contributor.author | Rajkhowa, R | |
| dc.contributor.author | Wang, X | |
| dc.contributor.author | Yazawa, K | |
| dc.contributor.author | Zheng, Z | |
| dc.contributor.author | Numata, K | |
| dc.date.accessioned | 2023-01-19T00:13:33Z | |
| dc.date.available | 2023-01-19T00:13:33Z | |
| dc.date.issued | 2022-10-14 | |
| dc.identifier.citation | Sci Adv, 2022, 8, (41), pp. eabo6043 | |
| dc.identifier.issn | 2375-2548 | |
| dc.identifier.issn | 2375-2548 | |
| dc.identifier.uri | http://hdl.handle.net/10453/165163 | |
| dc.description.abstract | Spider silks are among the toughest known materials and thus provide models for renewable, biodegradable, and sustainable biopolymers. However, the entirety of their diversity still remains elusive, and silks that exceed the performance limits of industrial fibers are constantly being found. We obtained transcriptome assemblies from 1098 species of spiders to comprehensively catalog silk gene sequences and measured the mechanical, thermal, structural, and hydration properties of the dragline silks of 446 species. The combination of these silk protein genotype-phenotype data revealed essential contributions of multicomponent structures with major ampullate spidroin 1 to 3 paralogs in high-performance dragline silks and numerous amino acid motifs contributing to each of the measured properties. We hope that our global sampling, comprehensive testing, integrated analysis, and open data will provide a solid starting point for future biomaterial designs. | |
| dc.format | Print-Electronic | |
| dc.language | eng | |
| dc.publisher | American Association for the Advancement of Science (AAAS) | |
| dc.relation.ispartof | Sci Adv | |
| dc.relation.isbasedon | 10.1126/sciadv.abo6043 | |
| dc.rights | info:eu-repo/semantics/openAccess | |
| dc.title | 1000 spider silkomes: Linking sequences to silk physical properties. | |
| dc.type | Journal Article | |
| utslib.citation.volume | 8 | |
| utslib.location.activity | United States | |
| pubs.organisational-group | /University of Technology Sydney | |
| pubs.organisational-group | /University of Technology Sydney/Faculty of Engineering and Information Technology | |
| utslib.copyright.status | open_access | * |
| dc.date.updated | 2023-01-19T00:13:11Z | |
| pubs.issue | 41 | |
| pubs.publication-status | Published | |
| pubs.volume | 8 | |
| utslib.citation.issue | 41 |
Abstract:
Spider silks are among the toughest known materials and thus provide models for renewable, biodegradable, and sustainable biopolymers. However, the entirety of their diversity still remains elusive, and silks that exceed the performance limits of industrial fibers are constantly being found. We obtained transcriptome assemblies from 1098 species of spiders to comprehensively catalog silk gene sequences and measured the mechanical, thermal, structural, and hydration properties of the dragline silks of 446 species. The combination of these silk protein genotype-phenotype data revealed essential contributions of multicomponent structures with major ampullate spidroin 1 to 3 paralogs in high-performance dragline silks and numerous amino acid motifs contributing to each of the measured properties. We hope that our global sampling, comprehensive testing, integrated analysis, and open data will provide a solid starting point for future biomaterial designs.
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