Gonadal Atresia, Estrogen-Responsive, and Apoptosis-Specific mRNA Expression in Marine Mussels from the East China Coast: A Preliminary Study.

Zhu, J; Li, J; Chapman, EC; Shi, H; Ciocan, CM; Chen, K; Shi, X; Zhou, J; Sun, P; Zheng, Y; Rotchell, JM

Gonadal Atresia, Estrogen-Responsive, and Apoptosis-Specific mRNA Expression in Marine Mussels from the East China Coast: A Preliminary Study.

Zhu, J Li, J Chapman, EC Shi, H Ciocan, CM Chen, K Shi, X Zhou, J

Sun, P Zheng, Y Rotchell, JM

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Publisher:: SPRINGER
Publication Type:: Journal Article
Citation:: Bull Environ Contam Toxicol, 2022, 108, (6), pp. 1111-1117
Issue Date:: 2022-06

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Field	Value	Language
dc.contributor.author	Zhu, J
dc.contributor.author	Li, J
dc.contributor.author	Chapman, EC
dc.contributor.author	Shi, H
dc.contributor.author	Ciocan, CM
dc.contributor.author	Chen, K
dc.contributor.author	Shi, X
dc.contributor.author	Zhou, J https://orcid.org/0000-0003-1393-1608
dc.contributor.author	Sun, P
dc.contributor.author	Zheng, Y
dc.contributor.author	Rotchell, JM
dc.date.accessioned	2023-03-24T03:56:51Z
dc.date.available	2022-01-11
dc.date.available	2023-03-24T03:56:51Z
dc.date.issued	2022-06
dc.identifier.citation	Bull Environ Contam Toxicol, 2022, 108, (6), pp. 1111-1117
dc.identifier.issn	0007-4861
dc.identifier.issn	1432-0800
dc.identifier.uri	http://hdl.handle.net/10453/168320
dc.description.abstract	This preliminary survey analysed mussel atresia incidences, estrogen-responsive and apoptotic-specific molecular end points, and aqueous and gonadal levels of selected estrogens from the East China coast. Estrogen levels were low (e.g. < LOD-28.36 ng/L, < LOD-3.88 ng/g wet weight of tissue for BPA) relative to worldwide freshwater environments, but high oocyte follicle atresia incidences (up to 26.6%) occurred at selected sites. Expression of estrogen-responsive ER2 was significantly increased in males relative to females at sites with high atresia incidences in females. A second estrogen-responsive gene, V9, was significantly increased at two sites in April in females relative to males; the opposite was true for the remaining two sites. Apoptosis-specific genes (Bcl-2, fas) showed elevated expression in males relative to females at the site with the highest atresia incidence. These results provide coastal estrogen levels and the utility of several estrogen-specific molecular-level markers for marine mussels.
dc.format	Print-Electronic
dc.language	eng
dc.publisher	SPRINGER
dc.relation.ispartof	Bull Environ Contam Toxicol
dc.relation.isbasedon	10.1007/s00128-022-03461-2
dc.rights	info:eu-repo/semantics/openAccess
dc.subject	03 Chemical Sciences, 05 Environmental Sciences
dc.subject.classification	Environmental Sciences
dc.subject.mesh	Animals
dc.subject.mesh	Apoptosis
dc.subject.mesh	Bivalvia
dc.subject.mesh	Estrogens
dc.subject.mesh	Female
dc.subject.mesh	Gonads
dc.subject.mesh	Male
dc.subject.mesh	Mytilus
dc.subject.mesh	RNA, Messenger
dc.subject.mesh	Gonads
dc.subject.mesh	Animals
dc.subject.mesh	RNA, Messenger
dc.subject.mesh	Estrogens
dc.subject.mesh	Apoptosis
dc.subject.mesh	Female
dc.subject.mesh	Male
dc.subject.mesh	Bivalvia
dc.subject.mesh	Mytilus
dc.subject.mesh	Animals
dc.subject.mesh	Apoptosis
dc.subject.mesh	Bivalvia
dc.subject.mesh	Estrogens
dc.subject.mesh	Female
dc.subject.mesh	Gonads
dc.subject.mesh	Male
dc.subject.mesh	Mytilus
dc.subject.mesh	RNA, Messenger
dc.title	Gonadal Atresia, Estrogen-Responsive, and Apoptosis-Specific mRNA Expression in Marine Mussels from the East China Coast: A Preliminary Study.
dc.type	Journal Article
utslib.citation.volume	108
utslib.location.activity	United States
utslib.for	03 Chemical Sciences
utslib.for	05 Environmental Sciences
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Engineering and Information Technology
pubs.organisational-group	/University of Technology Sydney/Faculty of Engineering and Information Technology/School of Civil and Environmental Engineering
pubs.organisational-group	/University of Technology Sydney/Strength - CTWW - Centre for Technology in Water and Wastewater Treatment
utslib.copyright.status	open_access	*
dc.date.updated	2023-03-24T03:56:47Z
pubs.issue	6
pubs.publication-status	Published
pubs.volume	108
utslib.citation.issue	6

Abstract:

This preliminary survey analysed mussel atresia incidences, estrogen-responsive and apoptotic-specific molecular end points, and aqueous and gonadal levels of selected estrogens from the East China coast. Estrogen levels were low (e.g. < LOD-28.36 ng/L, < LOD-3.88 ng/g wet weight of tissue for BPA) relative to worldwide freshwater environments, but high oocyte follicle atresia incidences (up to 26.6%) occurred at selected sites. Expression of estrogen-responsive ER2 was significantly increased in males relative to females at sites with high atresia incidences in females. A second estrogen-responsive gene, V9, was significantly increased at two sites in April in females relative to males; the opposite was true for the remaining two sites. Apoptosis-specific genes (Bcl-2, fas) showed elevated expression in males relative to females at the site with the highest atresia incidence. These results provide coastal estrogen levels and the utility of several estrogen-specific molecular-level markers for marine mussels.

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http://hdl.handle.net/10453/168320