Medications in pregnancy: Impact on time to lactogenesis after parturition

Publication Type:
Journal Article
Journal of Pharmacy Practice and Research, 2008, 38 (3), pp. 205 - 208
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Background: Although the many factors that affect the initiation of lactation have been identified, the impact of medications on lactogenesis remains largely unknown. Aim: To explore the impact of medications used during pregnancy on time to lactogenesis after parturition. Method: Data were collected prospectively from women admitted to a metropolitan Sydney hospital for parturition. Information was obtained via a short interview with each patient, as well as from medical notes, drug charts and infant feeding charts. Results: The average time to lactogenesis was 68.9 hours (range 22.5-126). 39% of women experienced delayed lactogenesis. Observational results showed that the use of some medications during pregnancy may impact on the time to lactogenesis. Cigarette smoking during pregnancy and prolonged stage II vaginal delivery may also increase the time to lactogenesis. Conclusion: Several medications used during pregnancy may impact on time to lactogenesis but the biological plausibility is unknown.
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