Emerging Applications of Polymeric Nanoparticles in Tumor Targeting

Marwaha, MG; Awasthi, R; Marwaha, RK; Prasher, P; Gulati, M; Singh, SK; Anand, K; Gupta, G; Chellappan, DK; Dua, K; Dureja, H

Emerging Applications of Polymeric Nanoparticles in Tumor Targeting

Marwaha, MG Awasthi, R Marwaha, RK Prasher, P Gulati, M Singh, SK Anand, K Gupta, G Chellappan, DK Dua, K

Dureja, H

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Publisher:: Bentham Science Publishers
Publication Type:: Journal Article
Citation:: Current Nanoscience, 2022, 18, (5), pp. 677-696
Issue Date:: 2022-09-28

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Field	Value	Language
dc.contributor.author	Marwaha, MG
dc.contributor.author	Awasthi, R
dc.contributor.author	Marwaha, RK
dc.contributor.author	Prasher, P
dc.contributor.author	Gulati, M
dc.contributor.author	Singh, SK
dc.contributor.author	Anand, K
dc.contributor.author	Gupta, G
dc.contributor.author	Chellappan, DK
dc.contributor.author	Dua, K https://orcid.org/0000-0002-7507-1159
dc.contributor.author	Dureja, H
dc.date.accessioned	2023-04-10T11:32:33Z
dc.date.available	2023-04-10T11:32:33Z
dc.date.issued	2022-09-28
dc.identifier.citation	Current Nanoscience, 2022, 18, (5), pp. 677-696
dc.identifier.issn	1573-4137
dc.identifier.uri	http://hdl.handle.net/10453/169395
dc.description.abstract	<jats:sec> <jats:title>Abstract:</jats:title> <jats:p>Nanoparticles are well-established carriers for targeted delivery of bioactive polymeric nanoparticles (PNPs). They have attracted significant attention from pharmaceutical scientists globally due to their wide range of applications in the medical field. The encapsulation of drugs into the nanoparticles offer several unique characteristics leading to prolonged circulation, improved drug localization, and thus enhanced drug efficacy. It also provides a better understanding of the molecular basis of the disease. Nanoparticles allow efficient maintenance of medication cycles at the target site, with less exposure to normal cells and thus decreasing the rehabilitation period. Despite extensive developments in the field of nanotechnology, specifically in drug delivery, only a few nanotechnology-based products are currently available in the market. Thus, further advanced exploration is necessary to make nanoparticles useful for the betterment of mankind. This review is focused on recent advancements in pharmaceutical nanotechnology with special emphasis on polymers used for the preparation of PNPs and their emerging applications in tumor-targeting. This manuscript also highlights on the recent patents disclosing PNPs for tumor targeting.</jats:p> </jats:sec>
dc.language	en
dc.publisher	Bentham Science Publishers
dc.relation.ispartof	Current Nanoscience
dc.relation.isbasedon	10.2174/1573413718666220928114233
dc.rights	info:eu-repo/semantics/closedAccess
dc.subject	1007 Nanotechnology
dc.subject.classification	Nanoscience & Nanotechnology
dc.title	Emerging Applications of Polymeric Nanoparticles in Tumor Targeting
dc.type	Journal Article
utslib.citation.volume	18
utslib.for	1007 Nanotechnology
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Health
pubs.organisational-group	/University of Technology Sydney/Faculty of Health/Graduate School of Health
pubs.organisational-group	/University of Technology Sydney/Faculty of Health/Graduate School of Health/GSH.Pharmacy
utslib.copyright.status	closed_access	*
dc.date.updated	2023-04-10T11:32:32Z
pubs.issue	5
pubs.publication-status	Accepted
pubs.volume	18
utslib.citation.issue	5

Abstract:

Abstract: Nanoparticles are well-established carriers for targeted delivery of bioactive polymeric nanoparticles (PNPs). They have attracted significant attention from pharmaceutical scientists globally due to their wide range of applications in the medical field. The encapsulation of drugs into the nanoparticles offer several unique characteristics leading to prolonged circulation, improved drug localization, and thus enhanced drug efficacy. It also provides a better understanding of the molecular basis of the disease. Nanoparticles allow efficient maintenance of medication cycles at the target site, with less exposure to normal cells and thus decreasing the rehabilitation period. Despite extensive developments in the field of nanotechnology, specifically in drug delivery, only a few nanotechnology-based products are currently available in the market. Thus, further advanced exploration is necessary to make nanoparticles useful for the betterment of mankind. This review is focused on recent advancements in pharmaceutical nanotechnology with special emphasis on polymers used for the preparation of PNPs and their emerging applications in tumor-targeting. This manuscript also highlights on the recent patents disclosing PNPs for tumor targeting.

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http://hdl.handle.net/10453/169395