Three-dimensional numerical simulation of particle acoustophoresis: COMSOL implementation and case studies

Zareei, SM; Sepehrirahnama, S; Jamshidian, M; Ziaei-Rad, S

Three-dimensional numerical simulation of particle acoustophoresis: COMSOL implementation and case studies

Zareei, SM Sepehrirahnama, S

Jamshidian, M Ziaei-Rad, S

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Publisher:: SPRINGER
Publication Type:: Journal Article
Citation:: Engineering with Computers, 2023, 39, (1), pp. 735-750
Issue Date:: 2023-02-01

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Field	Value	Language
dc.contributor.author	Zareei, SM
dc.contributor.author	Sepehrirahnama, S https://orcid.org/0000-0002-3280-3321
dc.contributor.author	Jamshidian, M
dc.contributor.author	Ziaei-Rad, S
dc.date.accessioned	2023-04-18T01:56:32Z
dc.date.available	2023-04-18T01:56:32Z
dc.date.issued	2023-02-01
dc.identifier.citation	Engineering with Computers, 2023, 39, (1), pp. 735-750
dc.identifier.issn	0177-0667
dc.identifier.issn	1435-5663
dc.identifier.uri	http://hdl.handle.net/10453/169888
dc.description.abstract	As a microfluidic-based noncontact manipulation and separation technique, acoustophoresis is the motion of the particles or cells within a host fluid under the effect of acoustic waves. Wave scattering off the particle surface generates both acoustic radiation forces and interparticle interaction forces that move the particles relative to the host fluid and each other, respectively. In this paper, an implementation in the commercial finite element software COMSOL Multiphysics for three-dimensional simulations of particle acoustophoresis is presented. Case studies with various particle types including rigid, compressible, elastic, core–shell and different particle geometries including spherical and spheroidal particles as well as pair-particle are simulated. The simulation results are verified by comparing the scattered velocity potential around the particle and the acoustic forces on the particle, against the existing analytical solutions. Furthermore, the COMSOL Livelink for MATLAB is utilized to implement an incremental simulation algorithm for the particle migration under the effect of a standing wave in a microchannel, based on the Stokes drag formula. The acoustophoretic motion simulations are performed for single particle and pair-particle case studies to demonstrate the presented implementation capabilities in modeling multi-particle tracking in real applications.
dc.language	English
dc.publisher	SPRINGER
dc.relation.ispartof	Engineering with Computers
dc.relation.isbasedon	10.1007/s00366-022-01663-0
dc.rights	info:eu-repo/semantics/closedAccess
dc.subject	0102 Applied Mathematics, 0801 Artificial Intelligence and Image Processing, 0802 Computation Theory and Mathematics
dc.subject.classification	Design Practice & Management
dc.title	Three-dimensional numerical simulation of particle acoustophoresis: COMSOL implementation and case studies
dc.type	Journal Article
utslib.citation.volume	39
utslib.for	0102 Applied Mathematics
utslib.for	0801 Artificial Intelligence and Image Processing
utslib.for	0802 Computation Theory and Mathematics
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Engineering and Information Technology
utslib.copyright.status	closed_access	*
dc.date.updated	2023-04-18T01:56:31Z
pubs.issue	1
pubs.publication-status	Published
pubs.volume	39
utslib.citation.issue	1

Abstract:

As a microfluidic-based noncontact manipulation and separation technique, acoustophoresis is the motion of the particles or cells within a host fluid under the effect of acoustic waves. Wave scattering off the particle surface generates both acoustic radiation forces and interparticle interaction forces that move the particles relative to the host fluid and each other, respectively. In this paper, an implementation in the commercial finite element software COMSOL Multiphysics for three-dimensional simulations of particle acoustophoresis is presented. Case studies with various particle types including rigid, compressible, elastic, core–shell and different particle geometries including spherical and spheroidal particles as well as pair-particle are simulated. The simulation results are verified by comparing the scattered velocity potential around the particle and the acoustic forces on the particle, against the existing analytical solutions. Furthermore, the COMSOL Livelink for MATLAB is utilized to implement an incremental simulation algorithm for the particle migration under the effect of a standing wave in a microchannel, based on the Stokes drag formula. The acoustophoretic motion simulations are performed for single particle and pair-particle case studies to demonstrate the presented implementation capabilities in modeling multi-particle tracking in real applications.

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http://hdl.handle.net/10453/169888