Role of human papillomavirus in the etiology of head and neck cancer

Tran, N; Rose, BR; O'Brien, CJ

Role of human papillomavirus in the etiology of head and neck cancer

Tran, N

Rose, BR O'Brien, CJ

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Publication Type:: Journal Article
Citation:: Head and Neck, 2007, 29 (1), pp. 64 - 70
Issue Date:: 2007-01-01

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Field	Value	Language
dc.contributor.author	Tran, N https://orcid.org/0000-0001-7747-2530	en_US
dc.contributor.author	Rose, BR	en_US
dc.contributor.author	O'Brien, CJ	en_US
dc.date.issued	2007-01-01	en_US
dc.identifier.citation	Head and Neck, 2007, 29 (1), pp. 64 - 70	en_US
dc.identifier.issn	1043-3074	en_US
dc.identifier.uri	http://hdl.handle.net/10453/16998
dc.description.abstract	Head and neck cancer is the world's sixth most common cancer, but despite advances in treatment, there has been no significant decline in the mortality rate. In recent years, there has been mounting epidemiologic and experimental evidence of a role for human papillomavirus (HPV) as the etiologic agent of a subset of head and neck cancers. The association is strongest for oropharyngeal cancers, especially those of the tonsil. HPV 16 is invariably the predominant type. HPV-positive cancers have been shown to be biologically distinct, clustering among nonsmokers and light drinkers, and have been associated with a favorable prognosis. This review examines the current findings of HPV in head and neck cancers and discusses implications for developing new treatments. © 2006 Wiley Periodicals, Inc.	en_US
dc.relation.ispartof	Head and Neck	en_US
dc.relation.isbasedon	10.1002/hed.20460	en_US
dc.subject.classification	Otorhinolaryngology	en_US
dc.subject.mesh	Humans	en_US
dc.subject.mesh	Papillomaviridae	en_US
dc.subject.mesh	Head and Neck Neoplasms	en_US
dc.subject.mesh	Prognosis	en_US
dc.subject.mesh	Risk Factors	en_US
dc.title	Role of human papillomavirus in the etiology of head and neck cancer	en_US
dc.type	Journal Article
utslib.citation.volume	1	en_US
utslib.citation.volume	29	en_US
utslib.for	1103 Clinical Sciences	en_US
utslib.for	1105 Dentistry	en_US
dc.location.activity	ISI:000243030500011	en_US
dc.location.activity	Washington, DC, USA
dc.location.activity	United States
pubs.embargo.period	Not known	en_US
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Engineering and Information Technology
pubs.organisational-group	/University of Technology Sydney/Faculty of Engineering and Information Technology/School of Biomedical Engineering
pubs.organisational-group	/University of Technology Sydney/Strength - CHT - Health Technologies
utslib.copyright.status	closed_access
pubs.issue	1	en_US
pubs.publication-status	Published	en_US
pubs.volume	29	en_US

Abstract:

Head and neck cancer is the world's sixth most common cancer, but despite advances in treatment, there has been no significant decline in the mortality rate. In recent years, there has been mounting epidemiologic and experimental evidence of a role for human papillomavirus (HPV) as the etiologic agent of a subset of head and neck cancers. The association is strongest for oropharyngeal cancers, especially those of the tonsil. HPV 16 is invariably the predominant type. HPV-positive cancers have been shown to be biologically distinct, clustering among nonsmokers and light drinkers, and have been associated with a favorable prognosis. This review examines the current findings of HPV in head and neck cancers and discusses implications for developing new treatments. © 2006 Wiley Periodicals, Inc.

Please use this identifier to cite or link to this item:

http://hdl.handle.net/10453/16998