It's all about plant derived natural phytoconstituents and phytonanomedicine to control skin cancer

Ashique, S; Afzal, O; Hussain, A; Zeyaullah, M; Altamimi, MA; Mishra, N; Ahmad, MF; Dua, K; Altamimi, ASA; Anand, K

It's all about plant derived natural phytoconstituents and phytonanomedicine to control skin cancer

Ashique, S Afzal, O Hussain, A Zeyaullah, M Altamimi, MA Mishra, N Ahmad, MF Dua, K

Altamimi, ASA Anand, K

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Publisher:: Elsevier
Publication Type:: Journal Article
Citation:: Journal of Drug Delivery Science and Technology, 2023, 84, pp. 104495
Issue Date:: 2023-06-01

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Field	Value	Language
dc.contributor.author	Ashique, S
dc.contributor.author	Afzal, O
dc.contributor.author	Hussain, A
dc.contributor.author	Zeyaullah, M
dc.contributor.author	Altamimi, MA
dc.contributor.author	Mishra, N
dc.contributor.author	Ahmad, MF
dc.contributor.author	Dua, K https://orcid.org/0000-0002-7507-1159
dc.contributor.author	Altamimi, ASA
dc.contributor.author	Anand, K
dc.date.accessioned	2023-05-20T09:45:05Z
dc.date.available	2023-05-20T09:45:05Z
dc.date.issued	2023-06-01
dc.identifier.citation	Journal of Drug Delivery Science and Technology, 2023, 84, pp. 104495
dc.identifier.issn	1773-2247
dc.identifier.uri	http://hdl.handle.net/10453/170386
dc.description.abstract	Nanotechnology is an emerging science for controlling cutaneous cancer and related consequences like skin melanoma. Phyto nanomedicine facilitated drug targeting, penetration, and retention with mitigated side effects as a result of topical application. Data and information were collected from various kinds of literature. Data were critically evaluated and analyzed. Due to the immense structural diversity found in them, natural resources continue to be a valuable source of new and innovative chemical entities with potential therapeutic value. Skin cancer (SC) is a deadly disease and a global challenge for healthcare professionals. Considering the frequent emergence of drug resistance, new drug discovery and clinical success are expensive and long-term processes. Therefore, phytochemicals emerged as a new window for therapeutic alternatives with convincing outcomes. These phytoconstituents and phytonanomedicines demonstrated to control SC through diverse mechanistic signaling pathways either by up-regulation or down-regulation. These have been explored in several in vitro and in vivo models. In this review, we addressed causes, pathology, and treatment options using phytonanomedicine or phytoconstituents to control SC followed by mechanistic perspectives. Perspectives on the most important phytochemicals and nanomedicines and their therapeutic potential are included in the current review.
dc.language	en
dc.publisher	Elsevier
dc.relation.ispartof	Journal of Drug Delivery Science and Technology
dc.relation.isbasedon	10.1016/j.jddst.2023.104495
dc.rights	info:eu-repo/semantics/closedAccess
dc.subject	1115 Pharmacology and Pharmaceutical Sciences
dc.subject.classification	Pharmacology & Pharmacy
dc.title	It's all about plant derived natural phytoconstituents and phytonanomedicine to control skin cancer
dc.type	Journal Article
utslib.citation.volume	84
utslib.for	1115 Pharmacology and Pharmaceutical Sciences
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Health
pubs.organisational-group	/University of Technology Sydney/Faculty of Health/Graduate School of Health
pubs.organisational-group	/University of Technology Sydney/Faculty of Health/Graduate School of Health/GSH.Pharmacy
utslib.copyright.status	closed_access	*
dc.date.updated	2023-05-20T09:45:00Z
pubs.publication-status	Accepted
pubs.volume	84

Abstract:

Nanotechnology is an emerging science for controlling cutaneous cancer and related consequences like skin melanoma. Phyto nanomedicine facilitated drug targeting, penetration, and retention with mitigated side effects as a result of topical application. Data and information were collected from various kinds of literature. Data were critically evaluated and analyzed. Due to the immense structural diversity found in them, natural resources continue to be a valuable source of new and innovative chemical entities with potential therapeutic value. Skin cancer (SC) is a deadly disease and a global challenge for healthcare professionals. Considering the frequent emergence of drug resistance, new drug discovery and clinical success are expensive and long-term processes. Therefore, phytochemicals emerged as a new window for therapeutic alternatives with convincing outcomes. These phytoconstituents and phytonanomedicines demonstrated to control SC through diverse mechanistic signaling pathways either by up-regulation or down-regulation. These have been explored in several in vitro and in vivo models. In this review, we addressed causes, pathology, and treatment options using phytonanomedicine or phytoconstituents to control SC followed by mechanistic perspectives. Perspectives on the most important phytochemicals and nanomedicines and their therapeutic potential are included in the current review.

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http://hdl.handle.net/10453/170386