LIVING WITH HEART FAILURE AND MULTIMORBIDITY: SEX-BASED DIFFERENCES IN DISEASE BURDEN

Koirala, B; Liu, X; Lim, A; Benjasirisan, C; Himmelfarb, CD; Davidson, P

LIVING WITH HEART FAILURE AND MULTIMORBIDITY: SEX-BASED DIFFERENCES IN DISEASE BURDEN

Koirala, B Liu, X Lim, A Benjasirisan, C Himmelfarb, CD Davidson, P

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Publisher:: Oxford University Press (OUP)
Publication Type:: Journal Article
Citation:: Innovation in Aging, 2023, 7, (Suppl 1), pp. 923-924
Issue Date:: 2023-12-21

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Field	Value	Language
dc.contributor.author	Koirala, B
dc.contributor.author	Liu, X
dc.contributor.author	Lim, A
dc.contributor.author	Benjasirisan, C
dc.contributor.author	Himmelfarb, CD
dc.contributor.author	Davidson, P https://orcid.org/0000-0003-2050-1534
dc.date.accessioned	2024-01-15T05:51:25Z
dc.date.available	2024-01-15T05:51:25Z
dc.date.issued	2023-12-21
dc.identifier.citation	Innovation in Aging, 2023, 7, (Suppl 1), pp. 923-924
dc.identifier.issn	2399-5300
dc.identifier.issn	2399-5300
dc.identifier.uri	http://hdl.handle.net/10453/174480
dc.description.abstract	<jats:title>Abstract</jats:title> <jats:p>Heart failure (HF) is one of the leading causes of hospitalization and discharge diagnosis. People with HF present an average of six co-morbid conditions and are mostly older women. Comorbidity or multimorbidity in HF, increases the risk for poor health outcomes, significantly affecting the progression, severity, and complexity of management and care outcomes. This study aimed to examine the sex differences in disease burden among individuals living with multimorbidity. The study is an ongoing cohort study collecting socio-demographic, clinical, and outcome data at baseline, 30 days, and 1-year follow-up. Adults aged 50 years and older living with HF and multimorbidity, defined as the presence of HF and one more chronic condition identified as a common list of comorbidities were recruited using an electronic patient portal. Disease burden data were collected using a modified disease burden impact scale consisting of comorbid conditions included in the eligibility criteria. A preliminary analysis of 406 participants (mean [SD] age = 69.6[9.7] years; 49% female) at baseline found that females (67.7 [9.2] years) were significantly younger than males (71.6 [9.9] years) and females (28.1 [15.2]) had significantly higher disease burden scores compared to males (22.0 [13.6]). An adjusted analysis found females had 3 times higher disease burden scores than males (beta=3.32; 95% confidence interval [CI] = 0.44-6.20, p= 0.024), after controlling for sociodemographic characteristics, social support, resilience, and quality of life. Effective multimorbidity management program requires consideration of both sex and gender-based differences, particularly among older women.</jats:p>
dc.language	en
dc.publisher	Oxford University Press (OUP)
dc.relation.ispartof	Innovation in Aging
dc.relation.isbasedon	10.1093/geroni/igad104.2968
dc.rights	info:eu-repo/semantics/closedAccess
dc.subject.classification	3202 Clinical sciences
dc.title	LIVING WITH HEART FAILURE AND MULTIMORBIDITY: SEX-BASED DIFFERENCES IN DISEASE BURDEN
dc.type	Journal Article
utslib.citation.volume	7
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Health
pubs.organisational-group	/University of Technology Sydney/Faculty of Health/IMPACCT
utslib.copyright.status	closed_access	*
dc.date.updated	2024-01-15T05:51:24Z
pubs.issue	Suppl 1
pubs.publication-status	Published
pubs.volume	7
utslib.citation.issue	Suppl 1

Abstract:

Abstract Heart failure (HF) is one of the leading causes of hospitalization and discharge diagnosis. People with HF present an average of six co-morbid conditions and are mostly older women. Comorbidity or multimorbidity in HF, increases the risk for poor health outcomes, significantly affecting the progression, severity, and complexity of management and care outcomes. This study aimed to examine the sex differences in disease burden among individuals living with multimorbidity. The study is an ongoing cohort study collecting socio-demographic, clinical, and outcome data at baseline, 30 days, and 1-year follow-up. Adults aged 50 years and older living with HF and multimorbidity, defined as the presence of HF and one more chronic condition identified as a common list of comorbidities were recruited using an electronic patient portal. Disease burden data were collected using a modified disease burden impact scale consisting of comorbid conditions included in the eligibility criteria. A preliminary analysis of 406 participants (mean [SD] age = 69.6[9.7] years; 49% female) at baseline found that females (67.7 [9.2] years) were significantly younger than males (71.6 [9.9] years) and females (28.1 [15.2]) had significantly higher disease burden scores compared to males (22.0 [13.6]). An adjusted analysis found females had 3 times higher disease burden scores than males (beta=3.32; 95% confidence interval [CI] = 0.44-6.20, p= 0.024), after controlling for sociodemographic characteristics, social support, resilience, and quality of life. Effective multimorbidity management program requires consideration of both sex and gender-based differences, particularly among older women.

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http://hdl.handle.net/10453/174480