High-risk lifestyle and all-cause mortality in older Australians with stroke: A data linkage study

Peng, W; Maguire, J; Hayen, A; Adams, J; Sibbritt, D

High-risk lifestyle and all-cause mortality in older Australians with stroke: A data linkage study

Peng, W

Maguire, J

Hayen, A

Adams, J

Sibbritt, D

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Publisher:: Nakladatelske Stredisko CLSJE Purkyne
Publication Type:: Conference Proceeding
Citation:: European Journal of Public Health, 2020, 30, (5)
Issue Date:: 2020-10-15

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Field	Value	Language
dc.contributor.author	Peng, W https://orcid.org/0000-0001-9747-2466
dc.contributor.author	Maguire, J https://orcid.org/0000-0001-5722-8311
dc.contributor.author	Hayen, A https://orcid.org/0000-0003-4046-8030
dc.contributor.author	Adams, J https://orcid.org/0000-0002-9901-5717
dc.contributor.author	Sibbritt, D https://orcid.org/0000-0003-3561-9447
dc.date	2020-10-12
dc.date.accessioned	2024-03-24T23:32:27Z
dc.date.available	2024-03-24T23:32:27Z
dc.date.issued	2020-10-15
dc.identifier.citation	European Journal of Public Health, 2020, 30, (5)
dc.identifier.issn	1210-7778
dc.identifier.issn	1464-360X
dc.identifier.uri	http://hdl.handle.net/10453/177062
dc.description.abstract	Abstract Background Stroke prevention via lifestyle modification is a public health priority in developed countries. Few studies have examined the association of high-risk lifestyle factors with long-term mortality of stroke survivors. Therefore, this study aims to explore the effect of key lifestyle factors on all-cause mortality after stroke. Methods Sample is derived from the 45 and Up Study, the largest ongoing study in the Southern Hemisphere focusing on the health of people aged 45 years and older living in NSW, Australia. The lifestyle data in the 45 and Up Study between 2006 to 2015 were linked with data from the NSW Registry of Births, Deaths and Marriages, NSW Cause of Death Unit Record File, and NSW Admitted Patient Data Collection by the Centre for Health Record Linkage. We defined a high-risk lifestyle as no vigorous exercise, smokers, or > 10 alcoholic drinks/week. Multivariate Cox regression model is used to examine the effect of high-risk lifestyle on survival using 10-year all-cause mortality as the main outcome, adjusted for key confounders. Results We analysed information on 8410 adults with a stroke event occurring prior to the baseline 45 and Up Study, and 31% of them died in 10 years. 6219 participants were identified as having a high-risk lifestyle at baseline. Being a current smoker and without vigorous exercise were associated with 41% (95% CI: 16%, 73%) and 52% (95% CI: 30%, 78%) increase in the likelihood of death in 10 years, respectively. However, high-risk alcohol drinking was not significantly associated with survival. Of note, having cardiovascular-related comorbidities showed greater risks of mortality (HR range, 3.6-7.2). Conclusions High-risk lifestyle factors were associated with an increased risk of long-term all-cause mortality, suggesting that enhancing public health initiatives to promote 'healthy' lifestyle behaviours can be of great benefit to stroke survivors. Key messages It is essential for stroke survivors to maintain a healthy lifestyle to delay all-cause mortality. Stroke survivors with high-risk lifestyle may be associated with increased likelihood of death if they have comorbidities such as diabetes and hypertension.
dc.language	en
dc.publisher	Nakladatelske Stredisko CLSJE Purkyne
dc.relation	National Stroke Foundation
dc.relation.ispartof	European Journal of Public Health
dc.relation.isbasedon	10.1093/eurpub/ckaa166.1119
dc.rights	info:eu-repo/semantics/openAccess
dc.subject	1117 Public Health and Health Services
dc.subject.classification	Toxicology
dc.subject.classification	4206 Public health
dc.title	High-risk lifestyle and all-cause mortality in older Australians with stroke: A data linkage study
dc.type	Conference Proceeding
utslib.citation.volume	30
utslib.location.activity	Virtual
utslib.for	1117 Public Health and Health Services
pubs.organisational-group	University of Technology Sydney
pubs.organisational-group	University of Technology Sydney/Faculty of Health
pubs.organisational-group	University of Technology Sydney/Strength - CHSP - Health Services and Practice
pubs.organisational-group	University of Technology Sydney/Faculty of Health/Public Health
pubs.organisational-group	University of Technology Sydney/Strength - ARCCIM - Australian Research Centre in Complementary & Integrative Medicine
utslib.copyright.status	open_access	*
pubs.consider-herdc	false
dc.date.updated	2024-03-24T23:32:26Z
pubs.finish-date	2020-10-16
pubs.issue	5
pubs.publication-status	Published
pubs.start-date	2020-10-12
pubs.volume	30
utslib.citation.issue	5

Abstract:

Abstract Background Stroke prevention via lifestyle modification is a public health priority in developed countries. Few studies have examined the association of high-risk lifestyle factors with long-term mortality of stroke survivors. Therefore, this study aims to explore the effect of key lifestyle factors on all-cause mortality after stroke. Methods Sample is derived from the 45 and Up Study, the largest ongoing study in the Southern Hemisphere focusing on the health of people aged 45 years and older living in NSW, Australia. The lifestyle data in the 45 and Up Study between 2006 to 2015 were linked with data from the NSW Registry of Births, Deaths and Marriages, NSW Cause of Death Unit Record File, and NSW Admitted Patient Data Collection by the Centre for Health Record Linkage. We defined a high-risk lifestyle as no vigorous exercise, smokers, or > 10 alcoholic drinks/week. Multivariate Cox regression model is used to examine the effect of high-risk lifestyle on survival using 10-year all-cause mortality as the main outcome, adjusted for key confounders. Results We analysed information on 8410 adults with a stroke event occurring prior to the baseline 45 and Up Study, and 31% of them died in 10 years. 6219 participants were identified as having a high-risk lifestyle at baseline. Being a current smoker and without vigorous exercise were associated with 41% (95% CI: 16%, 73%) and 52% (95% CI: 30%, 78%) increase in the likelihood of death in 10 years, respectively. However, high-risk alcohol drinking was not significantly associated with survival. Of note, having cardiovascular-related comorbidities showed greater risks of mortality (HR range, 3.6-7.2). Conclusions High-risk lifestyle factors were associated with an increased risk of long-term all-cause mortality, suggesting that enhancing public health initiatives to promote 'healthy' lifestyle behaviours can be of great benefit to stroke survivors. Key messages It is essential for stroke survivors to maintain a healthy lifestyle to delay all-cause mortality. Stroke survivors with high-risk lifestyle may be associated with increased likelihood of death if they have comorbidities such as diabetes and hypertension.

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http://hdl.handle.net/10453/177062