A comparison of three analytical techniques for the measurement of steroidal estrogens in environmental water samples

Grover, DP; Zhang, ZL; Readman, JW; Zhou, JL

A comparison of three analytical techniques for the measurement of steroidal estrogens in environmental water samples

Grover, DP Zhang, ZL Readman, JW Zhou, JL

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Publication Type:: Journal Article
Citation:: Talanta, 2009, 78 (3), pp. 1204 - 1210
Issue Date:: 2009-05-15

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Field	Value	Language
dc.contributor.author	Grover, DP	en_US
dc.contributor.author	Zhang, ZL	en_US
dc.contributor.author	Readman, JW	en_US
dc.contributor.author	Zhou, JL https://orcid.org/0000-0003-1393-1608	en_US
dc.date.available	2008-12-22	en_US
dc.date.issued	2009-05-15	en_US
dc.identifier.citation	Talanta, 2009, 78 (3), pp. 1204 - 1210	en_US
dc.identifier.issn	0039-9140	en_US
dc.identifier.uri	http://hdl.handle.net/10453/33707
dc.identifier.uri	http://hdl.handle.net/10453/28156
dc.description.abstract	Research into the analysis and monitoring of steroidal estrogens has grown significantly over the last decade, resulting in the emergence of a range of applicable techniques. In this study, three popular techniques, gas chromatography-mass spectrometry (GC-MS), gas chromatography-tandem mass spectrometry (GC-MS-MS) and liquid chromatography-tandem mass spectrometry (LC-MS-MS) for the analysis of three highly potent steroidal estrogens in the aquatic environment have been compared. It has been observed that overall, the three techniques appear comparable in generating similar estrogen concentrations for river and effluent samples. Of the three techniques, the GC-MS technique is the simplest to operate, but fails to detect the estrogens at the lower-end of environmentally relevant concentrations. The tandem MS techniques are more selective than MS, and therefore able to detect lower concentration levels of the three steroidal estrogens of interest. However, the LC-MS-MS technique is more susceptible to matrix interferences for the analysis of samples, resulting in a reduction of the signal-to-noise ratio and a subsequent reduction in reliability and stability compared to GC-MS-MS. With the GC-MS-MS technique offering increased selectivity, the lowest limits of detection, and no false positive identification, it is recommended to be the preferred analytical technique for routine analysis of estrogens in environmental water samples. © 2009 Elsevier B.V. All rights reserved.	en_US
dc.relation.ispartof	Talanta	en_US
dc.relation.isbasedon	10.1016/j.talanta.2008.12.049	en_US
dc.subject.classification	Analytical Chemistry	en_US
dc.subject.mesh	Estrogens	en_US
dc.subject.mesh	Water Pollutants	en_US
dc.subject.mesh	Chromatography, Liquid	en_US
dc.subject.mesh	Rivers	en_US
dc.subject.mesh	Gas Chromatography-Mass Spectrometry	en_US
dc.subject.mesh	Tandem Mass Spectrometry	en_US
dc.subject.mesh	Chemistry Techniques, Analytical	en_US
dc.title	A comparison of three analytical techniques for the measurement of steroidal estrogens in environmental water samples	en_US
dc.type	Journal Article
utslib.citation.volume	3	en_US
utslib.citation.volume	78	en_US
utslib.for	0399 Other Chemical Sciences	en_US
utslib.for	0301 Analytical Chemistry	en_US
pubs.embargo.period	Not known	en_US
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Engineering and Information Technology
pubs.organisational-group	/University of Technology Sydney/Faculty of Engineering and Information Technology/School of Civil and Environmental Engineering
pubs.organisational-group	/University of Technology Sydney/Strength - CTWW - Centre for Technology in Water and Wastewater Treatment
utslib.copyright.status	closed_access
pubs.issue	3	en_US
pubs.publication-status	Published	en_US
pubs.volume	78	en_US

Abstract:

Research into the analysis and monitoring of steroidal estrogens has grown significantly over the last decade, resulting in the emergence of a range of applicable techniques. In this study, three popular techniques, gas chromatography-mass spectrometry (GC-MS), gas chromatography-tandem mass spectrometry (GC-MS-MS) and liquid chromatography-tandem mass spectrometry (LC-MS-MS) for the analysis of three highly potent steroidal estrogens in the aquatic environment have been compared. It has been observed that overall, the three techniques appear comparable in generating similar estrogen concentrations for river and effluent samples. Of the three techniques, the GC-MS technique is the simplest to operate, but fails to detect the estrogens at the lower-end of environmentally relevant concentrations. The tandem MS techniques are more selective than MS, and therefore able to detect lower concentration levels of the three steroidal estrogens of interest. However, the LC-MS-MS technique is more susceptible to matrix interferences for the analysis of samples, resulting in a reduction of the signal-to-noise ratio and a subsequent reduction in reliability and stability compared to GC-MS-MS. With the GC-MS-MS technique offering increased selectivity, the lowest limits of detection, and no false positive identification, it is recommended to be the preferred analytical technique for routine analysis of estrogens in environmental water samples. © 2009 Elsevier B.V. All rights reserved.

Please use this identifier to cite or link to this item:

http://hdl.handle.net/10453/28156