Connecting rules from paired miRNA and mRNA expression data sets of HCV patients to detect both inverse and positive regulatory relationships

BioMed Central
Publication Type:
Journal Article
BMC Genomics, 2015, 16 (Suppl 2)
Issue Date:
Full metadata record
Files in This Item:
Filename Description Size
Thumbnail1471-2164-16-S2-S11.pdf2.98 MB
Adobe PDF
Intensive research based on the inverse expression relationship has been undertaken to discover the miRNA-mRNA regulatory modules involved in the infection of Hepatitis C virus (HCV), the leading cause of chronic liver diseases. However, biological studies in other fields have found that inverse expression relationship is not the only regulatory relationship between miRNAs and their targets, and some miRNAs can positively regulate a mRNA by binding at the 5’ UTR of the mRNA.
Please use this identifier to cite or link to this item:

Not enough data to produce graph