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Author(s)
2013-04-01
Phosphodiesterase 4 inhibitors augment the ability of formoterol to enhance glucocorticoid-dependent gene transcription in human airway epithelial cells: A novel mechanism for the clinical efficacy of roflumilast in severe chronic obstructive pulmonary disease
Moodley, T
;
Wilson, SM
;
Joshi, T
;
Rider, CF
;
Sharma, P
;
Yan, D
;
Newton, R
;
Giembycz, MA
2015-05-01
Inhibitors of phosphodiesterase 4, but not phosphodiesterase 3, increase β<inf>2</inf>-agonist-induced expression of antiinflammatory mitogen-activated protein kinase phosphatase 1 in airway smooth muscle cells
Patel, BS
;
Prabhala, P
;
Oliver, BG
;
Ammit, AJ
2017-04-01
Roflumilast N-oxide in combination with formoterol enhances the antiinflammatory effect of dexamethasone in airway smooth muscle cells
Patel, BS
;
Rahman, MM
;
Baehring, G
;
Xenaki, D
;
Tang, FSM
;
Oliver, BG
;
Ammit, AJ
2016-06-01
Theophylline represses IL-8 secretion from airway smooth muscle cells independently of phosphodiesterase inhibition: Novel role as a protein phosphatase 2A activator
Patel, BS
;
Rahman, MM
;
Rumzhum, NN
;
Oliver, BG
;
Verrills, NM
;
Ammit, AJ
2019-05-01
Prostaglandin E<inf>2</inf>, but not cAMP nor β<inf>2</inf>-agonists, induce tristetraprolin (TTP) in human airway smooth muscle cells
Bradbury, P
;
Patel, BS
;
Cidem, A
;
Nader, CP
;
Oliver, BG
;
Ammit, AJ
2012-02-01
β <inf>2</inf>-agonists upregulate PDE4 mRNA but not protein or activity in human airway smooth muscle cells from asthmatic and nonasthmatic volunteers
Niimi, K
;
Ge, Q
;
Moir, LM
;
Ammit, AJ
;
Trian, T
;
Burgess, JK
;
Black, JL
;
Oliver, BGG
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Subject
6
Humans
5
Myocytes, Smooth Muscle
5
RNA, Messenger
4
Adrenergic beta-2 Receptor Agonists
4
Cells, Cultured
4
Cyclic AMP
4
Dual Specificity Phosphatase 1
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Respiratory System
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Up-Regulation
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