Choice of collimator for cardiac SPET when resolution compensation is included in iterative reconstruction.

Lau, YH; Hutton, BF; Beekman, FJ

Choice of collimator for cardiac SPET when resolution compensation is included in iterative reconstruction.

Lau, YH Hutton, BF Beekman, FJ

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Publication Type:: Journal Article
Citation:: Eur J Nucl Med, 2001, 28 (1), pp. 39 - 47
Issue Date:: 2001-01

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Field	Value	Language
dc.contributor.author	Lau, YH	en_US
dc.contributor.author	Hutton, BF	en_US
dc.contributor.author	Beekman, FJ	en_US
dc.date.issued	2001-01	en_US
dc.identifier.citation	Eur J Nucl Med, 2001, 28 (1), pp. 39 - 47	en_US
dc.identifier.issn	0340-6997	en_US
dc.identifier.uri	http://hdl.handle.net/10453/4468
dc.description.abstract	In clinical cardiac single-photon emission tomography (SPET) studies, collimators of different spatial resolution and geometric efficiency are available for imaging. In selecting the appropriate collimator for clinical use, there is a trade-off between spatial resolution, which can limit the contrast of the reconstructed image, and detection efficiency, which determines the noise in the image. Our objective was to assess which collimator is best suited for cardiac SPET when reconstruction is performed with and without compensation for distance-dependent resolution (CDR). The dynamic MCAT thorax phantom was used to simulate 180 degree technetium-99m cardiac data, acquired using either a general-purpose (GP) or high-resolution (HR) collimator. For GP and HR, the resolution at 15 cm was 11.5 mm and 9.5 mm respectively, and the corresponding relative efficiency was 1.0 and 0.52 respectively. Distance-dependent resolution, attenuation and noise were included in the projection data; scatter was not included. Ordered subsets expectation maximisation reconstruction (subset size 4) was performed with and without CDR. Results were evaluated by comparing the myocardial recovery coefficient and contrast between myocardium and ventricle relative to the original phantom, each plotted for different noise levels corresponding to increasing iteration number. The study demonstrated that, without CDR, HR gave the best results. However, for any given noise level with CDR, GP gave superior recovery and contrast. These findings were confirmed in a physical phantom study. Results suggest that improved reconstruction can be achieved using a GP collimator in combination with resolution compensation.	en_US
dc.language	eng	en_US
dc.relation.ispartof	Eur J Nucl Med	en_US
dc.relation.isbasedon	10.1007/s002590000387	en_US
dc.subject.classification	Nuclear Medicine & Medical Imaging	en_US
dc.subject.mesh	Heart	en_US
dc.subject.mesh	Humans	en_US
dc.subject.mesh	Tomography, Emission-Computed, Single-Photon	en_US
dc.subject.mesh	Algorithms	en_US
dc.subject.mesh	Models, Anatomic	en_US
dc.subject.mesh	Computer Simulation	en_US
dc.subject.mesh	Image Processing, Computer-Assisted	en_US
dc.title	Choice of collimator for cardiac SPET when resolution compensation is included in iterative reconstruction.	en_US
dc.type	Journal Article
utslib.citation.volume	1	en_US
utslib.citation.volume	28	en_US
utslib.location.activity	Germany	en_US
utslib.for	0299 Other Physical Sciences	en_US
utslib.for	1103 Clinical Sciences	en_US
pubs.embargo.period	Not known	en_US
pubs.organisational-group	/University of Technology Sydney
utslib.copyright.status	closed_access
pubs.issue	1	en_US
pubs.publication-status	Published	en_US
pubs.volume	28	en_US

Abstract:

In clinical cardiac single-photon emission tomography (SPET) studies, collimators of different spatial resolution and geometric efficiency are available for imaging. In selecting the appropriate collimator for clinical use, there is a trade-off between spatial resolution, which can limit the contrast of the reconstructed image, and detection efficiency, which determines the noise in the image. Our objective was to assess which collimator is best suited for cardiac SPET when reconstruction is performed with and without compensation for distance-dependent resolution (CDR). The dynamic MCAT thorax phantom was used to simulate 180 degree technetium-99m cardiac data, acquired using either a general-purpose (GP) or high-resolution (HR) collimator. For GP and HR, the resolution at 15 cm was 11.5 mm and 9.5 mm respectively, and the corresponding relative efficiency was 1.0 and 0.52 respectively. Distance-dependent resolution, attenuation and noise were included in the projection data; scatter was not included. Ordered subsets expectation maximisation reconstruction (subset size 4) was performed with and without CDR. Results were evaluated by comparing the myocardial recovery coefficient and contrast between myocardium and ventricle relative to the original phantom, each plotted for different noise levels corresponding to increasing iteration number. The study demonstrated that, without CDR, HR gave the best results. However, for any given noise level with CDR, GP gave superior recovery and contrast. These findings were confirmed in a physical phantom study. Results suggest that improved reconstruction can be achieved using a GP collimator in combination with resolution compensation.

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http://hdl.handle.net/10453/4468