The continuing evolution of forensic DNA profiling  from STRs to SNPs

Daniel, R; Walsh, SJ

The continuing evolution of forensic DNA profiling from STRs to SNPs

Daniel, R Walsh, SJ

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Publisher:: Australian Academy of Forensic Sciences
Citation:: Daniel, R. and Walsh, S. 2006 'The continuing evolution of forensic DNA profiling from STRs to SNPs', Australian Journal of Forensic Sciences, vol. 38, no. 2, pp. 59-74.
Issue Date:: 2006

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Field	Value	Language
dc.contributor.author	Daniel, R	en_US
dc.contributor.author	Walsh, SJ	en_US
dc.date.accessioned	2009-06-26T04:22:43Z
dc.date.available	2009-06-26T04:22:43Z
dc.date.issued	2006	en_US
dc.identifier	2006005837	en_US
dc.identifier.citation	Daniel, R. and Walsh, S. 2006 'The continuing evolution of forensic DNA profiling from STRs to SNPs', Australian Journal of Forensic Sciences, vol. 38, no. 2, pp. 59-74.	en_US
dc.identifier.issn	0045-0618	en_US
dc.identifier.other	C1	en_US
dc.identifier.uri	http://hdl.handle.net/10453/824
dc.description.abstract	Forensic DNA profiling combines the dynamic science of molecular genetics with the complexities of the forensic context. As such, throughout its twenty-year history, this field has seen continuous change, remarkable growth and an associated level of public, legal and scientific scrutiny previously unknown in the forensic sciences. Almost ubiquitously, applications of forensic DNA profiling have focused on resolving the identity of the donor of a particular sample of biological evidence. This is typically achieved by targeting noncoding microsatellite (or STR) loci. Recently however, novel techniques have emerged that target different DNA polymorphisms and allow scientists to address additional questions about the evidence, beyond the identification of source. In this short review we introduce an example of this next generation of forensic DNA techniques, single nucleotide polymorphisms (or SNPs). We summarise their molecular and technological basis and the manner in which they may be applied to further advance the capabilities of forensic investigators.	en_US
dc.publisher	Australian Academy of Forensic Sciences	en_US
dc.relation.ispartof	Australian Journal of Forensic Sciences	en_US
dc.relation.isbasedon	http//dx.doi.org/10.1080/00450610609410633	en_US
dc.title	The continuing evolution of forensic DNA profiling from STRs to SNPs	en_US
utslib.citation.volume	38	en_US
utslib.citation.number	2	en_US
utslib.location	Canberra ACT Australia	en_US
utslib.citation.startpage	59	en_US
utslib.citation.endpage	74	en_US
utslib.identifier.org	Science	en_US
utslib.copyright.status	closed_access

Abstract:

Forensic DNA profiling combines the dynamic science of molecular genetics with the complexities of the forensic context. As such, throughout its twenty-year history, this field has seen continuous change, remarkable growth and an associated level of public, legal and scientific scrutiny previously unknown in the forensic sciences. Almost ubiquitously, applications of forensic DNA profiling have focused on resolving the identity of the donor of a particular sample of biological evidence. This is typically achieved by targeting noncoding microsatellite (or STR) loci. Recently however, novel techniques have emerged that target different DNA polymorphisms and allow scientists to address additional questions about the evidence, beyond the identification of source. In this short review we introduce an example of this next generation of forensic DNA techniques, single nucleotide polymorphisms (or SNPs). We summarise their molecular and technological basis and the manner in which they may be applied to further advance the capabilities of forensic investigators.

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http://hdl.handle.net/10453/824