Expression Of A Gi-Coupled Receptor In The Heart Causes Impaired Ca2+ Handling, Myofilament Injury, And Dilated Cardiomyopathy

McCloskey, D; Turcato, S; Wang, G; Turnbull, L; Zhu, B; Bambino, T; Nguyen, A; Lovett, D; Nissenson, R; Karliner, J; Baker, A

Expression Of A Gi-Coupled Receptor In The Heart Causes Impaired Ca2+ Handling, Myofilament Injury, And Dilated Cardiomyopathy

McCloskey, D Turcato, S Wang, G Turnbull, L Zhu, B Bambino, T Nguyen, A Lovett, D Nissenson, R Karliner, J Baker, A

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Publisher:: Amer Physiological Soc
Publication Type:: Journal Article
Citation:: Mccloskey Dt et al. 2008, 'Expression Of A Gi-Coupled Receptor In The Heart Causes Impaired Ca2+ Handling, Myofilament Injury, And Dilated Cardiomyopathy', Amer Physiological Soc, vol. 294, no. 1, pp. H205-H212.
Issue Date:: 2008

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Field	Value	Language
dc.contributor.author	McCloskey, D	en_US
dc.contributor.author	Turcato, S	en_US
dc.contributor.author	Wang, G	en_US
dc.contributor.author	Turnbull, L	en_US
dc.contributor.author	Zhu, B	en_US
dc.contributor.author	Bambino, T	en_US
dc.contributor.author	Nguyen, A	en_US
dc.contributor.author	Lovett, D	en_US
dc.contributor.author	Nissenson, R	en_US
dc.contributor.author	Karliner, J	en_US
dc.contributor.author	Baker, A	en_US
dc.date.accessioned	2010-05-28T09:44:57Z
dc.date.available	2010-05-28T09:44:57Z
dc.date.issued	2008	en_US
dc.identifier	2008006506	en_US
dc.identifier.citation	Mccloskey Dt et al. 2008, 'Expression Of A Gi-Coupled Receptor In The Heart Causes Impaired Ca2+ Handling, Myofilament Injury, And Dilated Cardiomyopathy', Amer Physiological Soc, vol. 294, no. 1, pp. H205-H212.	en_US
dc.identifier.issn	0363-6135	en_US
dc.identifier.other	C1UNSUBMIT	en_US
dc.identifier.uri	http://hdl.handle.net/10453/8706
dc.description.abstract	Increased signaling by G(i)-coupled receptors has been implicated in dilated cardiomyopathy. To investigate the mechanisms, we used transgenic mice that develop dilated cardiomyopathy after conditional expression of a cardiac-targeted G(i)-coupled recept	en_US
dc.publisher	Amer Physiological Soc	en_US
dc.relation.ispartof	American Journal Of Physiology-Heart And Circulato...	en_US
dc.relation.ispartof	Verified OK	en_US
dc.relation.isbasedon	http://dx.doi.org/10.1152/ajpheart.00829.2007	en_US
dc.subject	matrix metalloproteinase-2; sarco(endo)plasmic reticulum Ca2+-ATPase; contraction; {kappa}-opioid receptor; conditional expression	en_US
dc.subject.classification	Biochemistry and Cell Biology	en_US
dc.title	Expression Of A Gi-Coupled Receptor In The Heart Causes Impaired Ca2+ Handling, Myofilament Injury, And Dilated Cardiomyopathy	en_US
dc.type	Journal article
utslib.citation.volume	294	en_US
utslib.citation.number	1	en_US
utslib.location	Bethesda, USA	en_US
utslib.citation.startpage	H205	en_US
utslib.citation.endpage	H212	en_US
utslib.identifier.org	SCI.Institute for Biotechnology of Infectious Diseases	en_US
utslib.for	060100	en_US
utslib.percentage	100	en_US
dc.location.activity	ISI:000252261200025	en_US
utslib.copyright.status	closed_access

Abstract:

Increased signaling by G(i)-coupled receptors has been implicated in dilated cardiomyopathy. To investigate the mechanisms, we used transgenic mice that develop dilated cardiomyopathy after conditional expression of a cardiac-targeted G(i)-coupled recept

Please use this identifier to cite or link to this item:

http://hdl.handle.net/10453/8706