Browsing by Author Tyndall, JDA

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Showing results 1 to 8 of 8
Issue DateTitleAuthor(s)
1-Apr-2012The active site residue V266 of chlamydial HtrA is critical for substrate binding during both in vitro and in vivo conditionsGloeckl, S; Tyndall, JDA; Stansfield, SH; Timms, P; Huston, WM
17-Aug-2016Chlamydia Serine Protease Inhibitor, targeting HtrA, as a New Treatment for Koala Chlamydia infectionLawrence, A; Fraser, T; Gillett, A; Tyndall, JDA; Timms, P; Polkinghorne, A; Huston, WM
30-Sep-2015A Chlamydia trachomatis strain with a chemically generated amino acid substitution (P370L) in the cthtrA gene shows reduced elementary body production Microbial genetics, genomics and proteomicsMarsh, JW; Wee, BA; Tyndall, JDA; Lott, WB; Bastidas, RJ; Caldwell, HD; Valdivia, RH; Kari, L; Huston, WM
1-Jul-2017CtHtrA: The lynchpin of the chlamydial surface and a promising therapeutic targetMarsh, JW; Ong, VA; Lott, WB; Timms, P; Tyndall, JDA; Huston, WM
1-Aug-2013Identification of a serine protease inhibitor which causes inclusion vacuole reduction and is lethal to Chlamydia trachomatisGloeckl, S; Ong, VA; Patel, P; Tyndall, JDA; Timms, P; Beagley, KW; Allan, JA; Armitage, CW; Turnbull, L; Whitchurch, CB; Merdanovic, M; Ehrmann, M; Powers, JC; Oleksyszyn, J; Verdoes, M; Bogyo, M; Huston, WM
1-Dec-2013Proteolytic activation of Chlamydia trachomatis HTRA is mediated by PDZ1 domain interactions with protease domain loops L3 and LC and beta strand β5Marsh, JW; Lott, WB; Tyndall, JDA; Huston, WWM
22-Mar-2018Stereochemical basis for the anti-chlamydial activity of the phosphonate protease inhibitor JO146Agbowuro, AA; Mazraani, R; McCaughey, LC; Huston, WM; Gamble, AB; Tyndall, JDA
8-Sep-2011Unique residues involved in activation of the multitasking protease/chaperone HtrA from Chlamydia trachomatisHuston, WM; Tyndall, JDA; Lott, WB; Stansfield, SH; Timms, P