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Issue DateTitleAuthor(s)
2021-11-24A microRNA-21-mediated SATB1/S100A9/NF-κB axis promotes chronic obstructive pulmonary disease pathogenesis.Kim, RY; Sunkara, KP; Bracke, KR; Jarnicki, AG; Donovan, C; Hsu, AC; Ieni, A; Beckett, EL; Galvão, I; Wijnant, S; Ricciardolo, FL; Di Stefano, A; Haw, TJ; Liu, G; Ferguson, AL; Palendira, U; Wark, PA; Conickx, G; Mestdagh, P; Brusselle, GG; Caramori, G; Foster, PS; Horvat, JC; Hansbro, PM
2016-07A pathogenic role for tumor necrosis factor-related apoptosis-inducing ligand in chronic obstructive pulmonary disease.Haw, TJ; Starkey, MR; Nair, PM; Pavlidis, S; Liu, G; Nguyen, DH; Hsu, AC; Hanish, I; Kim, RY; Collison, AM; Inman, MD; Wark, PA; Foster, PS; Knight, DA; Mattes, J; Yagita, H; Adcock, IM; Horvat, JC; Hansbro, PM
2020-07-29ACE2 Expression is elevated in Airway Epithelial Cells from aged and male donors but reduced in asthmaWark, PA; Pathinayake, PS; Kaiko, G; Nichol, K; Ali, A; Chen, L; Sutanto, EN; Garratt, LW; Sohal, SS; Lu, W; Eapen, MS; Oldmeadow, C; Bartlett, N; Reid, A; Veerati, P; C-Y.Hsu, A; Looi, K; Iosifidis, T; Stick, SM; Hansbro, PM; Kicic, A
2022-02-17Aim2 suppresses cigarette smoke-induced neutrophil recruitment, neutrophil caspase-1 activation and anti-Ly6G-mediated neutrophil depletion.Donovan, C; Kim, RY; Galvao, I; Jarnicki, AG; Brown, AC; Jones-Freeman, B; Gomez, HM; Wadhwa, R; Hortle, E; Jayaraman, R; Khan, H; Pickles, S; Sahu, P; Chimankar, V; Tu, X; Khadem Ali, M; Mayall, JR; Nguyen, DH; Budden, KF; Kumar, V; Schroder, K; Robertson, AA; Cooper, MA; Wark, PA; Oliver, BG; Horvat, JC; Hansbro, PM
2017-12-01Airway remodelling and inflammation in asthma are dependent on the extracellular matrix protein fibulin-1cLiu, G; Cooley, MA; Nair, PM; Donovan, C; Hsu, AC; Jarnicki, AG; Haw, TJ; Hansbro, NG; Ge, Q; Brown, AC; Tay, H; Foster, PS; Wark, PA; Horvat, JC; Bourke, JE; Grainge, CL; Argraves, WS; Oliver, BG; Knight, DA; Burgess, JK; Hansbro, PM
2020-04-23Crucial role for lung iron level and regulation in the pathogenesis and severity of asthma.Ali, MK; Kim, RY; Brown, AC; Mayall, JR; Karim, R; Pinkerton, JW; Liu, G; Martin, KL; Starkey, MR; Pillar, AL; Donovan, C; Pathinayake, PS; Carroll, OR; Trinder, D; Tay, HL; Badi, YE; Kermani, NZ; Guo, Y-K; Aryal, R; Mumby, S; Pavlidis, S; Adcock, IM; Weaver, J; Xenaki, D; Oliver, BG; Holliday, EG; Foster, PS; Wark, PA; Johnstone, DM; Milward, EA; Hansbro, PM; Horvat, JC
2019-01-01Enhancing tristetraprolin activity reduces the severity of cigarette smoke-induced experimental chronic obstructive pulmonary diseaseNair, PM; Starkey, MR; Haw, TJ; Liu, G; Collison, AM; Mattes, J; Wark, PA; Morris, JC; Verrills, NM; Clark, AR; Ammit, AJ; Hansbro, PM
2019-07-25Fibulin-1c regulates transforming growth factor–β activation in pulmonary tissue fibrosisLiu, G; Cooley, MA; Jarnicki, AG; Borghuis, T; Nair, PM; Tjin, G; Hsu, AC; Haw, TJ; Fricker, M; Harrison, CL; Jones, B; Hansbro, NG; Wark, PA; Horvat, JC; Scott Argraves, W; Oliver, BG; Knight, DA; Burgess, JK; Hansbro, PM
2019-07-01IL-22 and its receptors are increased in human and experimental COPD and contribute to pathogenesisStarkey, MR; Plank, MW; Casolari, P; Papi, A; Pavlidis, S; Guo, Y; Cameron, GJM; Haw, TJ; Tam, A; Obiedat, M; Donovan, C; Hansbro, NG; Nguyen, DH; Nair, PM; Kim, RY; Horvat, JC; Kaiko, GE; Durum, SK; Wark, PA; Sin, DD; Caramori, G; Adcock, IM; Foster, PS; Hansbro, PM
2016-07Impaired Antiviral Stress Granule and IFN-β Enhanceosome Formation Enhances Susceptibility to Influenza Infection in Chronic Obstructive Pulmonary Disease Epithelium.Hsu, AC-Y; Parsons, K; Moheimani, F; Knight, DA; Hansbro, PM; Fujita, T; Wark, PA
2018-08-02Influenza A virus infection dysregulates the expression of microRNA-22 and its targets; CD147 and HDAC4, in epithelium of asthmaticsMoheimani, F; Koops, J; Williams, T; Reid, AT; Hansbro, PM; Wark, PA; Knight, DA
2017-01-01MicroRNA profiling reveals a role for MicroRNA-218-5p in the pathogenesis of chronic obstructive pulmonary diseaseConickx, G; Mestdagh, P; Cobos, FA; Verhamme, FM; Maes, T; Vanaudenaerde, BM; Seys, LJM; Lahousse, L; Kim, RY; Hsu, AC; Wark, PA; Hansbro, PM; Joos, GF; Vandesompele, J; Bracke, KR; Brusselle, GG
2017-04-06MicroRNA-125a and -b inhibit A20 and MAVS to promote inflammation and impair antiviral response in COPDHsu, ACY; Dua, K; Starkey, MR; Haw, TJ; Nair, PM; Nichol, K; Zammit, N; Grey, ST; Baines, KJ; Foster, PS; Hansbro, PM; Wark, PA
2021-09-15Necroptosis Signaling Promotes Inflammation, Airway Remodeling, and Emphysema in Chronic Obstructive Pulmonary Disease.Lu, Z; Van Eeckhoutte, HP; Liu, G; Nair, PM; Jones, B; Gillis, CM; Nalkurthi, BC; Verhamme, F; Buyle-Huybrecht, T; Vandenabeele, P; Vanden Berghe, T; Brusselle, GG; Horvat, JC; Murphy, JM; Wark, PA; Bracke, KR; Fricker, M; Hansbro, PM
2013-01-01A new short-term mouse model of chronic obstructive pulmonary disease identifies a role for mast cell tryptase in pathogenesisBeckett, EL; Stevens, RL; Jarnicki, AG; Kim, RY; Hanish, I; Hansbro, NG; Deane, A; Keely, S; Horvat, JC; Yang, M; Oliver, BG; Van Rooijen, N; Inman, MD; Adachi, R; Soberman, RJ; Hamadi, S; Wark, PA; Foster, PS; Hansbro, PM
2018-05-01Persistent induction of goblet cell differentiation in the airways: Therapeutic approachesReid, AT; Veerati, PC; Gosens, R; Bartlett, NW; Wark, PA; Grainge, CL; Stick, SM; Kicic, A; Moheimani, F; Hansbro, PM; Knight, DA
2019-10-01RIPLET, and not TRIM25, is required for endogenous RIG-I-dependent antiviral responsesHayman, TJ; Hsu, AC; Kolesnik, TB; Dagley, LF; Willemsen, J; Tate, MD; Baker, PJ; Kershaw, NJ; Kedzierski, L; Webb, AI; Wark, PA; Kedzierska, K; Masters, SL; Belz, GT; Binder, M; Hansbro, PM; Nicola, NA; Nicholson, SE
2017-08-01Role for NLRP3 inflammasome-mediated, IL-1β-dependent responses in severe, steroid-resistant asthmaKim, RY; Pinkerton, JW; Essilfie, AT; Robertson, AAB; Baines, KJ; Brown, AC; Mayall, JR; Ali, MK; Starkey, MR; Hansbro, NG; Hirota, JA; Wood, LG; Simpson, JL; Knight, DA; Wark, PA; Gibson, PG; O'Neill, LAJ; Cooper, MA; Horvat, JC; Hansbro, PM
2019-01-01Roles for T/B lymphocytes and ILC2s in experimental chronic obstructive pulmonary diseaseDonovan, C; Starkey, MR; Kim, RY; Rana, BMJ; Barlow, JL; Jones, B; Haw, TJ; Mono Nair, P; Budden, K; Cameron, GJM; Horvat, JC; Wark, PA; Foster, PS; McKenzie, ANJ; Hansbro, PM
2020-10-01SARS-CoV-2 Spike protein promotes hyper-inflammatory response that can be ameliorated by Spike-antagonistic peptide and FDA-approved ER stress and MAP kinase inhibitors in vitroHsu, AC-Y; Wang, G; Reid, AT; Veerati, PC; Pathinayake, PS; Daly, K; Mayall, JR; Hansbro, PM; Horvat, JC; Wang, F; Wark, PA