Toward Label-Free Biosensing with Silicon Carbide: A Review

Cooper, O; Wang, B; Brown, CL; Tiralongo, J; Iacopi, F

Toward Label-Free Biosensing with Silicon Carbide: A Review

Cooper, O Wang, B Brown, CL Tiralongo, J Iacopi, F

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Publication Type:: Journal Article
Citation:: IEEE Access, 2016, 4 pp. 477 - 497
Issue Date:: 2016-01-01

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Field	Value	Language
dc.contributor.author	Cooper, O	en_US
dc.contributor.author	Wang, B	en_US
dc.contributor.author	Brown, CL	en_US
dc.contributor.author	Tiralongo, J	en_US
dc.contributor.author	Iacopi, F https://orcid.org/0000-0002-3196-0990	en_US
dc.date.issued	2016-01-01	en_US
dc.identifier.citation	IEEE Access, 2016, 4 pp. 477 - 497	en_US
dc.identifier.uri	http://hdl.handle.net/10453/116853
dc.description.abstract	© 2013 IEEE. Recent innovation in microelectrical-mechanical systems (MEMSs) and plasmonics-based technologies has opened up perspectives for label-free sensing of biological and chemical analytes. Label-free sensing would enable increased sensitivity and miniaturization capabilities for biosensing devices. Silicon carbide is a semiconductor material that happens to possess ideal properties for augmenting both the MEMS/nanoelectromechanical systems and the plasmonics routes. It has remarkable chemical and biological inertness resulting in a high degree of biocompatibility, as well as pronounced mechanical resilience. In addition, it is an efficient (low loss) plasmonic metamaterial. Its cubic polytype can be grown on silicon wafers, allowing easy micromachining into building blocks for sensing devices, scalable to large volume production. Finally, silicon carbide is an ideal starting material for a controlled, wafer-scale growth of graphene, offering an additional wealth of excellent properties for nanosensing. The combination of all of these capabilities makes silicon carbide an outstanding material platform for the realization of label-free, analyte-specific, and highly sensitive biochemical molecule detection systems. These technologies will open exciting horizons in terms of high throughput, efficient drug screening, and early pathogen detection.	en_US
dc.relation.ispartof	IEEE Access	en_US
dc.relation.isbasedon	10.1109/ACCESS.2016.2518190	en_US
dc.rights	info:eu-repo/semantics/openAccess
dc.title	Toward Label-Free Biosensing with Silicon Carbide: A Review	en_US
dc.type	Journal Article
utslib.citation.volume	4	en_US
utslib.for	100304 Industrial Biotechnology Diagnostics (incl. Biosensors)	en_US
utslib.for	08 Information and Computing Sciences	en_US
utslib.for	09 Engineering	en_US
utslib.for	10 Technology	en_US
pubs.embargo.period	Not known	en_US
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Engineering and Information Technology
pubs.organisational-group	/University of Technology Sydney/Faculty of Engineering and Information Technology/School of Electrical and Data Engineering
utslib.copyright.status	open_access	*
pubs.publication-status	Published	en_US
pubs.volume	4	en_US

Abstract:

© 2013 IEEE. Recent innovation in microelectrical-mechanical systems (MEMSs) and plasmonics-based technologies has opened up perspectives for label-free sensing of biological and chemical analytes. Label-free sensing would enable increased sensitivity and miniaturization capabilities for biosensing devices. Silicon carbide is a semiconductor material that happens to possess ideal properties for augmenting both the MEMS/nanoelectromechanical systems and the plasmonics routes. It has remarkable chemical and biological inertness resulting in a high degree of biocompatibility, as well as pronounced mechanical resilience. In addition, it is an efficient (low loss) plasmonic metamaterial. Its cubic polytype can be grown on silicon wafers, allowing easy micromachining into building blocks for sensing devices, scalable to large volume production. Finally, silicon carbide is an ideal starting material for a controlled, wafer-scale growth of graphene, offering an additional wealth of excellent properties for nanosensing. The combination of all of these capabilities makes silicon carbide an outstanding material platform for the realization of label-free, analyte-specific, and highly sensitive biochemical molecule detection systems. These technologies will open exciting horizons in terms of high throughput, efficient drug screening, and early pathogen detection.

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http://hdl.handle.net/10453/116853