Amniotic fluid embolism as a cause of maternal mortality in China between 1996 and 2013: A population-based retrospective study

Mu, Y; McDonnell, N; Li, Z; Liang, J; Wang, Y; Zhu, J; Sullivan, E

Amniotic fluid embolism as a cause of maternal mortality in China between 1996 and 2013: A population-based retrospective study

Mu, Y McDonnell, N Li, Z

Liang, J Wang, Y Zhu, J Sullivan, E

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Publication Type:: Journal Article
Citation:: BMC Pregnancy and Childbirth, 2016, 16 (1)
Issue Date:: 2016-10-19

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Field	Value	Language
dc.contributor.author	Mu, Y	en_US
dc.contributor.author	McDonnell, N	en_US
dc.contributor.author	Li, Z https://orcid.org/0000-0002-7622-150X	en_US
dc.contributor.author	Liang, J	en_US
dc.contributor.author	Wang, Y	en_US
dc.contributor.author	Zhu, J	en_US
dc.contributor.author	Sullivan, E https://orcid.org/0000-0002-8718-2753	en_US
dc.date.available	2016-10-11	en_US
dc.date.issued	2016-10-19	en_US
dc.identifier.citation	BMC Pregnancy and Childbirth, 2016, 16 (1)	en_US
dc.identifier.uri	http://hdl.handle.net/10453/116863
dc.description.abstract	© 2016 The Author(s). Background: To analyse the maternal mortality ratio, demographic and pregnancy related details in women who suffered a fatal amniotic fluid embolism (AFE) in China. Methods: A retrospective population based study using data collected as part of the National Maternal Mortality Surveillance System between 1996 and 2013. Data were collected onto a standardised form from women whose cause of death was listed as being secondary to AFE. Results: Records were available for 640 deaths. Over the 17 year period the maternal mortality ratio for AFE decreased from 4.4 per 100,000 births (95 % confidence interval (CI):2.72-6.12) to 1.9 per 100,000 births (95 % CI:1.35-2.54). Over the same period the proportion of maternal deaths secondary to AFE increased from 6.8 to 12.5 %. The mean age of women who died was 30.1 years and the onset of the AFE occurred prior to delivery in 39 %. The most prominent presenting features included premonitory symptoms (29 %), acute fetal compromise (28 %), maternal haemorrhage (16 %) and shortness of breath (15 %). Conclusions: Maternal mortality secondary to AFE has decreased in China, however at a slower rate than mortality secondary to other conditions. Active surveillance is recommended to assess case fatality rates, risk factors and other lessons specific to this population.	en_US
dc.relation.ispartof	BMC Pregnancy and Childbirth	en_US
dc.relation.isbasedon	10.1186/s12884-016-1106-6	en_US
dc.subject.classification	Obstetrics & Reproductive Medicine	en_US
dc.subject.mesh	Humans	en_US
dc.subject.mesh	Embolism, Amniotic Fluid	en_US
dc.subject.mesh	Maternal Mortality	en_US
dc.subject.mesh	Retrospective Studies	en_US
dc.subject.mesh	Pregnancy	en_US
dc.subject.mesh	Adult	en_US
dc.subject.mesh	China	en_US
dc.subject.mesh	Female	en_US
dc.subject.mesh	Young Adult	en_US
dc.title	Amniotic fluid embolism as a cause of maternal mortality in China between 1996 and 2013: A population-based retrospective study	en_US
dc.type	Journal Article
utslib.citation.volume	1	en_US
utslib.citation.volume	16	en_US
utslib.for	1110 Nursing	en_US
utslib.for	1114 Paediatrics and Reproductive Medicine	en_US
utslib.for	1117 Public Health and Health Services	en_US
pubs.embargo.period	Not known	en_US
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Health
pubs.organisational-group	/University of Technology Sydney/Faculty of Health/Public Health
utslib.copyright.status	open_access
pubs.issue	1	en_US
pubs.publication-status	Published	en_US
pubs.volume	16	en_US

Abstract:

© 2016 The Author(s). Background: To analyse the maternal mortality ratio, demographic and pregnancy related details in women who suffered a fatal amniotic fluid embolism (AFE) in China. Methods: A retrospective population based study using data collected as part of the National Maternal Mortality Surveillance System between 1996 and 2013. Data were collected onto a standardised form from women whose cause of death was listed as being secondary to AFE. Results: Records were available for 640 deaths. Over the 17 year period the maternal mortality ratio for AFE decreased from 4.4 per 100,000 births (95 % confidence interval (CI):2.72-6.12) to 1.9 per 100,000 births (95 % CI:1.35-2.54). Over the same period the proportion of maternal deaths secondary to AFE increased from 6.8 to 12.5 %. The mean age of women who died was 30.1 years and the onset of the AFE occurred prior to delivery in 39 %. The most prominent presenting features included premonitory symptoms (29 %), acute fetal compromise (28 %), maternal haemorrhage (16 %) and shortness of breath (15 %). Conclusions: Maternal mortality secondary to AFE has decreased in China, however at a slower rate than mortality secondary to other conditions. Active surveillance is recommended to assess case fatality rates, risk factors and other lessons specific to this population.

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http://hdl.handle.net/10453/116863