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Transperineal prostate biopsy under local vs general anaesthesia: a cost-effectiveness analysis.

Roberts, MJ Arora, S Yao, HH Hogan, D Dias, B O'Connell, HE Wetherell, D Zargar, H Kwok, M McGeorge, SP Pearce, A Yaxley, J Tuffaha, H

OBJECTIVES: To estimate the cost effectiveness of local anaesthetic (LA) transperineal prostate biopsy (TPB) compared to general anaesthetic (GA) TPB, considering both hospital/health system and so...

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Practical tips to fostering positive perceptions of and interest in general practice across medical training phases.

Yong, F Fox, J Martin, P Partanen, R Wallis, K McGrail, M

BACKGROUND: Servicing increasing healthcare demands requires a sufficient supply of general practitioners (GPs). However, heightened by pandemic conditions, critical and chronic shortages of GPs pe...

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Running in the heat similarly reduces lipid oxidation and peak oxygen consumption in trained runners and inactive individuals.

Mougin, L Macrae, HZ Henderson, A Cable, TG Taylor, L James, LJ Mears, SA

This study compared oxygen consumption and substrate oxidation while exercising in hot and temperate conditions in individuals with different physical activity statuses (i.e., inactive individuals ...

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Exploring the innovation landscape of ginger: Insights from patent documentation analysis

Matin, M Kapoor, B Gulati, M Mickael, ME Matin, FB Kamińska, A Bensz, J Sołdacki, D Wierzbicka, A Marcinkowska-Lesiak, M Fatimi, A Liu, HY Gan, RY Adamska, O Stolarczyk, A Horbańczuk, JO Jóźwik, A Atanasov, AG

Zingiber officinale, commonly known as ginger, holds a prominent place in both culinary and medicinal practices worldwide. This study is the first to present a comprehensive analysis of ginger-rela...

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Circulating Vaccine-Derived Poliovirus Type 2 (cVDPV2) Outbreak Response With Novel Oral Poliovirus Vaccine Type 2 (nOPV2), Sierra Leone's Experience

Kangbai, DM Sesay, EN Clemens-Kangbai, N Kemoh, AK Lansana, S Benya, H Nunie, A Kallon, JM Samuels, EG Clemens, A Jones, M Kanneh, BP James, PB Jimmy, AAN Kallay, MTM Sesay, T

Background: In March 2024, a circulating vaccine-derived poliovirus type 2 (cVDPV2) was isolated in environmental samples (ESs) collected at the Mabella Sawmill Bridge environmental surveillance (E...

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Are We Adequately Promoting Climate Change Adaptation to Address the Increasing Heatwaves Affecting the Elderly?

Hutton, A Maud, K Giggins, H Skipp, M Verdon-Kidd, D

Australia is a significant hotspot for heatwaves due to its geographical location and pronounced climatic variability, and heatwave exposure is expected to further increase in the future with anthr...

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Impact of birth weight on cardiovascular disease and mediating role of metabolic traits: a Mendelian randomisation study.

Zhuang, J Chen, S Long, J Ding, D Lam, LT Li, J An, R

BACKGROUND: Birth weight (BW) has been linked to cardiometabolic diseases, but causal associations with a comprehensive range of cardiovascular outcomes and underlying metabolic mechanisms remain u...

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Future-Proofing Malaysian Doctors: Integrating the United Nations Sustainable Development Goals and Planetary Health in Undergraduate Medical Education

Wong, RSY Pusparajah, P Hing, GB

The United Nations Sustainable Development Goals (SDGs) encompass 17 interconnected objectives aiming to eliminate hunger and end poverty by 2030. In contrast, planetary health examines the interpl...

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Antenatal dexamethasone for preterm birth and long-term health outcomes in children: a pilot follow-up cohort study of ACTION-I trial participants in Sylhet, Bangladesh

Sultana, S Jaben, IA Farha, T Roy, S Ahmed, S Homer, CSE Baqui, AH Vogel, JP

Background The WHO ACTION-I trial in 2020 demonstrated the short-term efficacy and safety of antenatal dexamethasone for women at risk of early preterm birth in low-resource settings. However, the ...

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Integrating clinical psychology and social care in oral cancer prevention & early detection: a needs assessment for interprofessional education

Sujir, N Ahmed, J Ramakrishna, A Mohammed, CA Unnikrishnan, B Gilbert, JHV Gangadhara, VK Monteiro, MJ

To address the challenges in the early diagnosis and prevention of oral cancer, it is essential to include clinical psychology and social care professionals in interprofessional healthcare teams. I...

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