Age at menarche and pregnancy-related pelvic pain

Kirkeby, MJ; Biering, K; Olsen, J; Juhl, M; Nohr, EA

Age at menarche and pregnancy-related pelvic pain

Kirkeby, MJ Biering, K Olsen, J Juhl, M Nohr, EA

Permalink

Publication Type:: Journal Article
Citation:: Journal of Obstetrics and Gynaecology Research, 2013, 39 (5), pp. 1037 - 1044
Issue Date:: 2013-05-01

Closed Access

	Filename	Description	Size
	Kirkeby_et_al-2013-Journal_of_Obstetrics_and_Gynaecology_Research.pdf	Published Version	166.41 kB	Adobe PDF	View/Open

Copyright Clearance Process

Recently Added
In Progress
Closed Access

This item is closed access and not available.

Full metadata record

Field	Value	Language
dc.contributor.author	Kirkeby, MJ	en_US
dc.contributor.author	Biering, K	en_US
dc.contributor.author	Olsen, J	en_US
dc.contributor.author	Juhl, M	en_US
dc.contributor.author	Nohr, EA	en_US
dc.date.available	2012-09-29	en_US
dc.date.issued	2013-05-01	en_US
dc.identifier.citation	Journal of Obstetrics and Gynaecology Research, 2013, 39 (5), pp. 1037 - 1044	en_US
dc.identifier.issn	1341-8076	en_US
dc.identifier.uri	http://hdl.handle.net/10453/117602
dc.description.abstract	Aim: Menarcheal age is a predictor of several complications related to pregnancy and diseases later in life.We aimed to study if menarcheal age is a risk factor for pregnancy-related pelvic pain. Material and Methods: A nested case-control study was conducted within the Danish National Birth Cohort, a cohort of pregnant women, recruited during 1996-2002, and their children. In the second trimester of pregnancy the women provided information about age at menarche and potential confounders. Selection of cases (n = 2227) was based on self-reported pelvic pain during pregnancy from an interview done 6 months post-partum. The controls (n = 2588) were randomly selected among women who did not report pelvic pain. We used logistic regression analysis to calculate odds ratios (OR) for pregnancy-related pelvic pain according to age at menarche. Results: In the cohort, 18.5% of all pregnant women reported pregnancy-related pelvic pain. Compared to women who were 12-14 years old at menarche, the adjusted OR for overall pelvic pain were 1.4 (95% confidence interval [CI] 1.1-1.7) in women 11 years or younger and 0.8 (95%CI 0.6-0.9) in women 15 years or older. The corresponding adjusted OR for severe pelvic pain were 1.6 (95%CI 1.3-2.0) and 0.7 (95%CI 0.6-0.9). When age was analyzed as a continuous variable, the odds for overall and severe pelvic pain decreased with 14% and 16%, respectively, for each increasing year. Conclusions: The risk of pregnancy-related pelvic pain decreased with increasing menarcheal age in an 'exposure-response' pattern. A low menarcheal age is a risk indicator and may be a risk factor for pregnancyrelated pelvic pain. © 2013 The Authors.	en_US
dc.relation.ispartof	Journal of Obstetrics and Gynaecology Research	en_US
dc.relation.isbasedon	10.1111/jog.12008	en_US
dc.subject.classification	Obstetrics & Reproductive Medicine	en_US
dc.subject.mesh	Humans	en_US
dc.subject.mesh	Pregnancy Complications	en_US
dc.subject.mesh	Pelvic Pain	en_US
dc.subject.mesh	Severity of Illness Index	en_US
dc.subject.mesh	Risk Factors	en_US
dc.subject.mesh	Case-Control Studies	en_US
dc.subject.mesh	Cohort Studies	en_US
dc.subject.mesh	Aging	en_US
dc.subject.mesh	Pregnancy	en_US
dc.subject.mesh	Menarche	en_US
dc.subject.mesh	Adult	en_US
dc.subject.mesh	Denmark	en_US
dc.subject.mesh	Female	en_US
dc.subject.mesh	Young Adult	en_US
dc.title	Age at menarche and pregnancy-related pelvic pain	en_US
dc.type	Journal Article
utslib.citation.volume	5	en_US
utslib.citation.volume	39	en_US
utslib.for	1114 Paediatrics and Reproductive Medicine	en_US
pubs.embargo.period	Not known	en_US
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Health
utslib.copyright.status	closed_access
pubs.issue	5	en_US
pubs.publication-status	Published	en_US
pubs.volume	39	en_US

Abstract:

Aim: Menarcheal age is a predictor of several complications related to pregnancy and diseases later in life.We aimed to study if menarcheal age is a risk factor for pregnancy-related pelvic pain. Material and Methods: A nested case-control study was conducted within the Danish National Birth Cohort, a cohort of pregnant women, recruited during 1996-2002, and their children. In the second trimester of pregnancy the women provided information about age at menarche and potential confounders. Selection of cases (n = 2227) was based on self-reported pelvic pain during pregnancy from an interview done 6 months post-partum. The controls (n = 2588) were randomly selected among women who did not report pelvic pain. We used logistic regression analysis to calculate odds ratios (OR) for pregnancy-related pelvic pain according to age at menarche. Results: In the cohort, 18.5% of all pregnant women reported pregnancy-related pelvic pain. Compared to women who were 12-14 years old at menarche, the adjusted OR for overall pelvic pain were 1.4 (95% confidence interval [CI] 1.1-1.7) in women 11 years or younger and 0.8 (95%CI 0.6-0.9) in women 15 years or older. The corresponding adjusted OR for severe pelvic pain were 1.6 (95%CI 1.3-2.0) and 0.7 (95%CI 0.6-0.9). When age was analyzed as a continuous variable, the odds for overall and severe pelvic pain decreased with 14% and 16%, respectively, for each increasing year. Conclusions: The risk of pregnancy-related pelvic pain decreased with increasing menarcheal age in an 'exposure-response' pattern. A low menarcheal age is a risk indicator and may be a risk factor for pregnancyrelated pelvic pain. © 2013 The Authors.

Please use this identifier to cite or link to this item:

http://hdl.handle.net/10453/117602