Oxygen for relief of dyspnoea in people with chronic obstructive pulmonary disease who would not qualify for home oxygen: A systematic review and meta-analysis

Uronis, HE; Ekström, MP; Currow, DC; McCrory, DC; Samsa, GP; Abernethy, AP

Oxygen for relief of dyspnoea in people with chronic obstructive pulmonary disease who would not qualify for home oxygen: A systematic review and meta-analysis

Uronis, HE Ekström, MP Currow, DC

McCrory, DC Samsa, GP Abernethy, AP

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Publication Type:: Journal Article
Citation:: Thorax, 2015, 70 (5), pp. 492 - 494
Issue Date:: 2015-05-01

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Field	Value	Language
dc.contributor.author	Uronis, HE	en_US
dc.contributor.author	Ekström, MP	en_US
dc.contributor.author	Currow, DC https://orcid.org/0000-0003-1988-1250	en_US
dc.contributor.author	McCrory, DC	en_US
dc.contributor.author	Samsa, GP	en_US
dc.contributor.author	Abernethy, AP	en_US
dc.date.available	2014-11-14	en_US
dc.date.issued	2015-05-01	en_US
dc.identifier.citation	Thorax, 2015, 70 (5), pp. 492 - 494	en_US
dc.identifier.issn	0040-6376	en_US
dc.identifier.uri	http://hdl.handle.net/10453/118609
dc.description.abstract	We searched MEDLINE, EMBASE and the Cochrane Controlled Trials Register to determine whether oxygen relieves dyspnoea in mildly or non-hypoxemic COPD and included 18 randomised controlled trials (431 participants) in the meta-analysis using Cochrane methodology. Oxygen therapy reduced dyspnoea when compared with medical air; standardised mean difference -0.37 (95% CI -0.50 to -0.24; I2=14%). In a priori subgroup and sensitivity analyses, dyspnoea was reduced by continuous oxygen during exertion but not short-burst oxygen therapy. Continuous exertional oxygen can relieve dyspnoea in mildly or non-hypoxemic COPD, but evidence from larger clinical trials is needed.	en_US
dc.relation.ispartof	Thorax	en_US
dc.relation.isbasedon	10.1136/thoraxjnl-2014-205720	en_US
dc.subject.classification	Respiratory System	en_US
dc.subject.mesh	Humans	en_US
dc.subject.mesh	Pulmonary Disease, Chronic Obstructive	en_US
dc.subject.mesh	Dyspnea	en_US
dc.subject.mesh	Oxygen Inhalation Therapy	en_US
dc.subject.mesh	Home Care Services	en_US
dc.title	Oxygen for relief of dyspnoea in people with chronic obstructive pulmonary disease who would not qualify for home oxygen: A systematic review and meta-analysis	en_US
dc.type	Journal Article
utslib.citation.volume	5	en_US
utslib.citation.volume	70	en_US
utslib.for	1103 Clinical Sciences	en_US
pubs.embargo.period	Not known	en_US
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Health
pubs.organisational-group	/University of Technology Sydney/Faculty of Health/IMPACCT
utslib.copyright.status	closed_access
pubs.issue	5	en_US
pubs.publication-status	Published	en_US
pubs.volume	70	en_US

Abstract:

We searched MEDLINE, EMBASE and the Cochrane Controlled Trials Register to determine whether oxygen relieves dyspnoea in mildly or non-hypoxemic COPD and included 18 randomised controlled trials (431 participants) in the meta-analysis using Cochrane methodology. Oxygen therapy reduced dyspnoea when compared with medical air; standardised mean difference -0.37 (95% CI -0.50 to -0.24; I2=14%). In a priori subgroup and sensitivity analyses, dyspnoea was reduced by continuous oxygen during exertion but not short-burst oxygen therapy. Continuous exertional oxygen can relieve dyspnoea in mildly or non-hypoxemic COPD, but evidence from larger clinical trials is needed.

Please use this identifier to cite or link to this item:

http://hdl.handle.net/10453/118609