Intermittent hypoxic resistance training: Is metabolic stress the key moderator?

Scott, BR; Slattery, KM; Dascombe, BJ

Intermittent hypoxic resistance training: Is metabolic stress the key moderator?

Scott, BR Slattery, KM Dascombe, BJ

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Publication Type:: Journal Article
Citation:: Medical Hypotheses, 2015, 84 (2), pp. 145 - 149
Issue Date:: 2015-01-01

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Field	Value	Language
dc.contributor.author	Scott, BR	en_US
dc.contributor.author	Slattery, KM	en_US
dc.contributor.author	Dascombe, BJ	en_US
dc.date.available	2014-12-03	en_US
dc.date.issued	2015-01-01	en_US
dc.identifier.citation	Medical Hypotheses, 2015, 84 (2), pp. 145 - 149	en_US
dc.identifier.issn	0306-9877	en_US
dc.identifier.uri	http://hdl.handle.net/10453/119384
dc.description.abstract	© 2014 Elsevier Ltd. Traditionally, researchers and practitioners have manipulated acute resistance exercise variables to elicit the desired responses to training. However, recent research indicates that altering the muscular environment during resistance training, namely by implementing a hypoxic stimulus, can augment muscle hypertrophy and strength. Intermittent hypoxic resistance training (IHRT), whereby participants inspire hypoxic air during resistance training, has been previously demonstrated to increase muscle cross-sectional area and maximum strength by significantly greater amounts than the equivalent training in normoxia. However, some recent evidence has provided conflicting results, reporting that the use of systemic hypoxia during resistance training provided no added benefit. While the definitive mechanisms that may augment muscular responses to IHRT are not yet fully understood, an increased metabolic stress is thought to be important for moderating many downstream processes related to hypertrophy. It is likely that methodological differences between conflicting IHRT studies have resulted in different degrees of metabolic stress during training, particularly when considering the inter-set recovery intervals used. Given that the most fundamental physiological stresses resulting from hypoxia are disturbances to oxidative metabolism, it becomes apparent that resistance training may only benefit from additional hypoxia if the exercise is structured to elicit a strong metabolic response. We hypothesize that for IHRT to be more effective in producing muscular hypertrophy and increasing strength than the equivalent normoxic training, exercise should be performed with relatively brief inter-set recovery periods, with the aim of providing a potent metabolic stimulus to enhance anabolic responses.	en_US
dc.relation.ispartof	Medical Hypotheses	en_US
dc.relation.isbasedon	10.1016/j.mehy.2014.12.001	en_US
dc.subject.classification	Neurology & Neurosurgery	en_US
dc.subject.mesh	Muscle, Skeletal	en_US
dc.subject.mesh	Humans	en_US
dc.subject.mesh	Models, Biological	en_US
dc.subject.mesh	Time Factors	en_US
dc.subject.mesh	Rest	en_US
dc.subject.mesh	Stress, Physiological	en_US
dc.subject.mesh	Resistance Training	en_US
dc.subject.mesh	Hypoxia	en_US
dc.title	Intermittent hypoxic resistance training: Is metabolic stress the key moderator?	en_US
dc.type	Journal Article
utslib.citation.volume	2	en_US
utslib.citation.volume	84	en_US
utslib.for	1106 Human Movement and Sports Sciences	en_US
utslib.for	11 Medical and Health Sciences	en_US
pubs.embargo.period	Not known	en_US
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Health
utslib.copyright.status	closed_access
pubs.issue	2	en_US
pubs.publication-status	Published	en_US
pubs.volume	84	en_US

Abstract:

© 2014 Elsevier Ltd. Traditionally, researchers and practitioners have manipulated acute resistance exercise variables to elicit the desired responses to training. However, recent research indicates that altering the muscular environment during resistance training, namely by implementing a hypoxic stimulus, can augment muscle hypertrophy and strength. Intermittent hypoxic resistance training (IHRT), whereby participants inspire hypoxic air during resistance training, has been previously demonstrated to increase muscle cross-sectional area and maximum strength by significantly greater amounts than the equivalent training in normoxia. However, some recent evidence has provided conflicting results, reporting that the use of systemic hypoxia during resistance training provided no added benefit. While the definitive mechanisms that may augment muscular responses to IHRT are not yet fully understood, an increased metabolic stress is thought to be important for moderating many downstream processes related to hypertrophy. It is likely that methodological differences between conflicting IHRT studies have resulted in different degrees of metabolic stress during training, particularly when considering the inter-set recovery intervals used. Given that the most fundamental physiological stresses resulting from hypoxia are disturbances to oxidative metabolism, it becomes apparent that resistance training may only benefit from additional hypoxia if the exercise is structured to elicit a strong metabolic response. We hypothesize that for IHRT to be more effective in producing muscular hypertrophy and increasing strength than the equivalent normoxic training, exercise should be performed with relatively brief inter-set recovery periods, with the aim of providing a potent metabolic stimulus to enhance anabolic responses.

Please use this identifier to cite or link to this item:

http://hdl.handle.net/10453/119384