Valuing health-related quality of life: An EQ-5D-5L value set for England

Devlin, NJ; Shah, KK; Feng, Y; Mulhern, B; van Hout, B

Valuing health-related quality of life: An EQ-5D-5L value set for England

Devlin, NJ Shah, KK Feng, Y Mulhern, B

van Hout, B

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Publication Type:: Journal Article
Citation:: Health Economics (United Kingdom), 2018, 27 (1), pp. 7 - 22
Issue Date:: 2018-01-01

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Field	Value	Language
dc.contributor.author	Devlin, NJ	en_US
dc.contributor.author	Shah, KK	en_US
dc.contributor.author	Feng, Y	en_US
dc.contributor.author	Mulhern, B https://orcid.org/0000-0003-3656-8063	en_US
dc.contributor.author	van Hout, B	en_US
dc.date.available	2017-06-23	en_US
dc.date.issued	2018-01-01	en_US
dc.identifier.citation	Health Economics (United Kingdom), 2018, 27 (1), pp. 7 - 22	en_US
dc.identifier.issn	1057-9230	en_US
dc.identifier.uri	http://hdl.handle.net/10453/124278
dc.description.abstract	© 2017 The Authors. Health Economics Published by John Wiley & Sons Ltd. A new version of the EQ-5D, the EQ-5D-5L, is available. The aim of this study is to produce a value set to support use of EQ-5D-5L data in decision-making. The study design followed an international research protocol. Randomly selected members of the English general public completed 10 time trade-off and 7 discrete choice experiment tasks in face-to-face interviews. A 20-parameter hybrid model was used to combine time trade-off and discrete choice experiment data to generate values for the 3,125 EQ-5D-5L health states. Valuation data are available for 996 respondents. Face validity of the data has been demonstrated, with more severe health states generally given lower values. Problems with pain/discomfort and anxiety/depression received the greatest weight. Compared to the existing EQ-5D-3L value set, there are considerably fewer “worse than dead” states (5.1%, compared with over one third), and the minimum value is higher. Values range from −0.285 (extreme problems on all dimensions) to 0.950 (for health states 11211 and 21111). Results have important implications for users of the EQ-5D-5L both in England and internationally. Quality-adjusted life year gains from interventions seeking to improve very poor health may be smaller using this value set and may previously have been overestimated.	en_US
dc.relation.ispartof	Health Economics (United Kingdom)	en_US
dc.relation.isbasedon	10.1002/hec.3564	en_US
dc.subject.classification	Health Policy & Services	en_US
dc.subject.mesh	Humans	en_US
dc.subject.mesh	Reproducibility of Results	en_US
dc.subject.mesh	Decision Making	en_US
dc.subject.mesh	Health Status	en_US
dc.subject.mesh	Quality-Adjusted Life Years	en_US
dc.subject.mesh	Research Design	en_US
dc.subject.mesh	Quality of Life	en_US
dc.subject.mesh	Adult	en_US
dc.subject.mesh	Aged	en_US
dc.subject.mesh	Middle Aged	en_US
dc.subject.mesh	England	en_US
dc.subject.mesh	Female	en_US
dc.subject.mesh	Male	en_US
dc.subject.mesh	Interviews as Topic	en_US
dc.subject.mesh	Surveys and Questionnaires	en_US
dc.title	Valuing health-related quality of life: An EQ-5D-5L value set for England	en_US
dc.type	Journal Article
utslib.citation.volume	1	en_US
utslib.citation.volume	27	en_US
utslib.for	140208 Health Economics	en_US
utslib.for	1117 Public Health and Health Services	en_US
utslib.for	1402 Applied Economics	en_US
utslib.for	1403 Econometrics	en_US
pubs.embargo.period	Not known	en_US
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Business
pubs.organisational-group	/University of Technology Sydney/Strength - CHERE - Centre for Health Economics Research and Evaluation
utslib.copyright.status	open_access
pubs.issue	1	en_US
pubs.publication-status	Published	en_US
pubs.volume	27	en_US

Abstract:

© 2017 The Authors. Health Economics Published by John Wiley & Sons Ltd. A new version of the EQ-5D, the EQ-5D-5L, is available. The aim of this study is to produce a value set to support use of EQ-5D-5L data in decision-making. The study design followed an international research protocol. Randomly selected members of the English general public completed 10 time trade-off and 7 discrete choice experiment tasks in face-to-face interviews. A 20-parameter hybrid model was used to combine time trade-off and discrete choice experiment data to generate values for the 3,125 EQ-5D-5L health states. Valuation data are available for 996 respondents. Face validity of the data has been demonstrated, with more severe health states generally given lower values. Problems with pain/discomfort and anxiety/depression received the greatest weight. Compared to the existing EQ-5D-3L value set, there are considerably fewer “worse than dead” states (5.1%, compared with over one third), and the minimum value is higher. Values range from −0.285 (extreme problems on all dimensions) to 0.950 (for health states 11211 and 21111). Results have important implications for users of the EQ-5D-5L both in England and internationally. Quality-adjusted life year gains from interventions seeking to improve very poor health may be smaller using this value set and may previously have been overestimated.

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http://hdl.handle.net/10453/124278