B Vitamin Complex and Chemotherapy-Induced Peripheral Neuropathy

Schloss, J; Colosimo, M

B Vitamin Complex and Chemotherapy-Induced Peripheral Neuropathy

Schloss, J Colosimo, M

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Publication Type:: Journal Article
Citation:: Current Oncology Reports, 2017, 19 (12)
Issue Date:: 2017-12-01

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Field	Value	Language
dc.contributor.author	Schloss, J	en_US
dc.contributor.author	Colosimo, M	en_US
dc.date.issued	2017-12-01	en_US
dc.identifier.citation	Current Oncology Reports, 2017, 19 (12)	en_US
dc.identifier.issn	1523-3790	en_US
dc.identifier.uri	http://hdl.handle.net/10453/126401
dc.description.abstract	© 2017, Springer Science+Business Media, LLC. Purpose of Review: The purpose of this mini review is to evaluate the literature on B vitamins and chemotherapy-induced peripheral neuropathy. Recent Findings: One hundred and five journal articles were evaluated and nine manuscripts were included. There was one in vitro, one was an animal and seven were human studies. The in vitro study was a safety study on vitamin B6 and oxaliplatin which was not directly related to CIPN. The animal study evaluated vitamin B3 on paclitaxel administration with positive results. The human studies varied using a vitamin B complex, vitamin B12 only and vitamin B6. Summary: Chemotherapy-induced peripheral neuropathy (CIPN) continues to plague patients and the medical fraternity. Currently, there are still no conclusive protective or treatment options. B vitamins have been found to play a role in CIPN prevention, but further studies are required to ascertain possible protection and treatment options.	en_US
dc.relation.ispartof	Current Oncology Reports	en_US
dc.relation.isbasedon	10.1007/s11912-017-0636-z	en_US
dc.subject.classification	Oncology & Carcinogenesis	en_US
dc.subject.mesh	Animals	en_US
dc.subject.mesh	Humans	en_US
dc.subject.mesh	Neoplasms	en_US
dc.subject.mesh	Peripheral Nervous System Diseases	en_US
dc.subject.mesh	Organoplatinum Compounds	en_US
dc.subject.mesh	Niacinamide	en_US
dc.subject.mesh	Vitamin B 12	en_US
dc.subject.mesh	Vitamin B Complex	en_US
dc.subject.mesh	Vitamin B 6	en_US
dc.subject.mesh	Oxaliplatin	en_US
dc.title	B Vitamin Complex and Chemotherapy-Induced Peripheral Neuropathy	en_US
dc.type	Journal Article
utslib.citation.volume	12	en_US
utslib.citation.volume	19	en_US
utslib.for	1112 Oncology and Carcinogenesis	en_US
pubs.embargo.period	Not known	en_US
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Health
utslib.copyright.status	closed_access
pubs.issue	12	en_US
pubs.publication-status	Published	en_US
pubs.volume	19	en_US

Abstract:

© 2017, Springer Science+Business Media, LLC. Purpose of Review: The purpose of this mini review is to evaluate the literature on B vitamins and chemotherapy-induced peripheral neuropathy. Recent Findings: One hundred and five journal articles were evaluated and nine manuscripts were included. There was one in vitro, one was an animal and seven were human studies. The in vitro study was a safety study on vitamin B6 and oxaliplatin which was not directly related to CIPN. The animal study evaluated vitamin B3 on paclitaxel administration with positive results. The human studies varied using a vitamin B complex, vitamin B12 only and vitamin B6. Summary: Chemotherapy-induced peripheral neuropathy (CIPN) continues to plague patients and the medical fraternity. Currently, there are still no conclusive protective or treatment options. B vitamins have been found to play a role in CIPN prevention, but further studies are required to ascertain possible protection and treatment options.

Please use this identifier to cite or link to this item:

http://hdl.handle.net/10453/126401