A noninvasive method to evaluate the degree of upper airway stenosis

Publication Type:
Journal Article
Citation:
Biomedical Engineering - Applications, Basis and Communications, 2017, 29 (5)
Issue Date:
2017-10-01
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A NONINVASIVE METHOD TO EVALUATE THE DEGREE OF UPPER AIRWAY STENOSIS (1).pdfPublished Version1.69 MB
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© 2017 National Taiwan University. Purpose: This paper presented a new approach to noninvasively evaluate the upper airway stenosis for obstructive sleep apnea syndrome (OSAS) patients. Methods: In the proposed method, thoracic and abdominal movements were selected to calculate the respiratory movement (RM) and to indicate the change of lung volume. Due to the cumulative effect of thermal sensor, the oronasal-Thermistor signal (T-flow) is applied to estimate the air mass change in lung. Based on the mathematical relationship, the "RM-T-flow curves", drawn by RM and T-flow, together with the correlation coefficients (rRM-TF) were used to analyze the upper airway stenosis. Results: This method was verified through portable monitoring (PM) based experiments, and numerical analysis of the polysomnography (PSG) data from 20 OSAS patients and 15 non-OSAS controls. Our results indicate the rRM-TF values decrease with the narrowing of the upper airway. At each sleep stage, the rRM-TF mean values of OSAS subjects are significantly (p<0.01) smaller than those of the controls. These facts demonstrate that the rRM-TF value can be used to quantify the upper airway stenosis and the analysis of "RM-T-flow curves" is an efficient way to assess upper airway condition associated with the breathing phase. Conclusions: As this method can be used in spontaneous sleep and home sleep testing, we believe it will benefit the popularity of the diagnosis and evaluation of OSAS.
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